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Page 1
Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Freda I, Exertier C, Barile A, Chaves-Sanjuan A, Vega MV, Isupov MN, Harmer NJ, Gugole E, Swuec P, Bolognesi M, Scipioni A, Savino C, Di Salvo ML, Contestabile R, Vallone B, Tramonti A, Montemiglio LC. Freda I, et al. Among authors: chaves sanjuan a. Nucleic Acids Res. 2023 Aug 25;51(15):8237-8254. doi: 10.1093/nar/gkad552. Nucleic Acids Res. 2023. PMID: 37378428 Free PMC article.
The guanine-exchange factor Ric8a binds to the Ca²⁺ sensor NCS-1 to regulate synapse number and neurotransmitter release.
Romero-Pozuelo J, Dason JS, Mansilla A, Baños-Mateos S, Sardina JL, Chaves-Sanjuán A, Jurado-Gómez J, Santana E, Atwood HL, Hernández-Hernández Á, Sánchez-Barrena MJ, Ferrús A. Romero-Pozuelo J, et al. J Cell Sci. 2014 Oct 1;127(Pt 19):4246-59. doi: 10.1242/jcs.152603. Epub 2014 Jul 29. J Cell Sci. 2014. PMID: 25074811 Free article.
Myocardial hypoxic stress mediates functional cardiac extracellular vesicle release.
Anselmo A, Frank D, Papa L, Viviani Anselmi C, Di Pasquale E, Mazzola M, Panico C, Clemente F, Soldani C, Pagiatakis C, Hinkel R, Thalmann R, Kozlik-Feldmann R, Miragoli M, Carullo P, Vacchiano M, Chaves-Sanjuan A, Santo N, Losi MA, Ferrari MC, Puca AA, Christiansen V, Seoudy H, Freitag-Wolf S, Frey N, Dempfle A, Mercola M, Esposito G, Briguori C, Kupatt C, Condorelli G. Anselmo A, et al. Among authors: chaves sanjuan a. Eur Heart J. 2021 Jul 21;42(28):2780-2792. doi: 10.1093/eurheartj/ehab247. Eur Heart J. 2021. PMID: 34104945
Recognition and Activation of the Plant AKT1 Potassium Channel by the Kinase CIPK23.
Sánchez-Barrena MJ, Chaves-Sanjuan A, Raddatz N, Mendoza I, Cortés Á, Gago F, González-Rubio JM, Benavente JL, Quintero FJ, Pardo JM, Albert A. Sánchez-Barrena MJ, et al. Plant Physiol. 2020 Apr;182(4):2143-2153. doi: 10.1104/pp.19.01084. Epub 2020 Feb 3. Plant Physiol. 2020. PMID: 32015077 Free PMC article.
Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.
Roca C, Martinez-González L, Daniel-Mozo M, Sastre J, Infantes L, Mansilla A, Chaves-Sanjuan A, González-Rubio JM, Gil C, Cañada FJ, Martinez A, Sanchez-Barrena MJ, Campillo NE. Roca C, et al. J Med Chem. 2018 Jul 26;61(14):5910-5921. doi: 10.1021/acs.jmedchem.8b00088. Epub 2018 Jul 17. J Med Chem. 2018. PMID: 29966094
Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Mansilla A, Chaves-Sanjuan A, Campillo NE, Semelidou O, Martínez-González L, Infantes L, González-Rubio JM, Gil C, Conde S, Skoulakis EM, Ferrús A, Martínez A, Sánchez-Barrena MJ. Mansilla A, et al. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E999-E1008. doi: 10.1073/pnas.1611089114. Epub 2017 Jan 24. Proc Natl Acad Sci U S A. 2017. PMID: 28119500 Free PMC article.
Structural basis of the regulatory mechanism of the plant CIPK family of protein kinases controlling ion homeostasis and abiotic stress.
Chaves-Sanjuan A, Sanchez-Barrena MJ, Gonzalez-Rubio JM, Moreno M, Ragel P, Jimenez M, Pardo JM, Martinez-Ripoll M, Quintero FJ, Albert A. Chaves-Sanjuan A, et al. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4532-41. doi: 10.1073/pnas.1407610111. Epub 2014 Oct 6. Proc Natl Acad Sci U S A. 2014. PMID: 25288725 Free PMC article.
28 results