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Nuclease activity and protein A release of Staphylococcus aureus clinical isolates determine the virulence in a murine model of acute lung infection.
Ludwig N, Thörner-van Almsick J, Mersmann S, Bardel B, Niemann S, Chasan AI, Schäfers M, Margraf A, Rossaint J, Kahl BC, Zarbock A, Block H. Ludwig N, et al. Among authors: chasan ai. Front Immunol. 2023 Oct 2;14:1259004. doi: 10.3389/fimmu.2023.1259004. eCollection 2023. Front Immunol. 2023. PMID: 37849760 Free PMC article.
CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow.
Fischer-Riepe L, Daber N, Schulte-Schrepping J, Véras De Carvalho BC, Russo A, Pohlen M, Fischer J, Chasan AI, Wolf M, Ulas T, Glander S, Schulz C, Skryabin B, Wollbrink Dipl-Ing A, Steingraeber N, Stremmel C, Koehle M, Gärtner F, Vettorazzi S, Holzinger D, Gross J, Rosenbauer F, Stoll M, Niemann S, Tuckermann J, Schultze JL, Roth J, Barczyk-Kahlert K. Fischer-Riepe L, et al. Among authors: chasan ai. J Allergy Clin Immunol. 2020 Nov;146(5):1137-1151. doi: 10.1016/j.jaci.2020.02.034. Epub 2020 Mar 19. J Allergy Clin Immunol. 2020. PMID: 32199911
Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity.
Liebmann M, Hucke S, Koch K, Eschborn M, Ghelman J, Chasan AI, Glander S, Schädlich M, Kuhlencord M, Daber NM, Eveslage M, Beyer M, Dietrich M, Albrecht P, Stoll M, Busch KB, Wiendl H, Roth J, Kuhlmann T, Klotz L. Liebmann M, et al. Among authors: chasan ai. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8017-E8026. doi: 10.1073/pnas.1721049115. Epub 2018 Aug 2. Proc Natl Acad Sci U S A. 2018. PMID: 30072431 Free PMC article.
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development.
Ruck T, Bock S, Pfeuffer S, Schroeter CB, Cengiz D, Marciniak P, Lindner M, Herrmann A, Liebmann M, Kovac S, Gola L, Rolfes L, Pawlitzki M, Opel N, Hahn T, Dannlowski U, Pap T, Luessi F, Schreiber JA, Wünsch B, Kuhlmann T, Seebohm G, Tackenberg B, Seja P, Döring F, Wischmeyer E, Chasan AI, Roth J, Klotz L, Meyer Zu Hörste G, Wiendl H, Marschall T, Floess S, Huehn J, Budde T, Bopp T, Bittner S, Meuth SG. Ruck T, et al. Among authors: chasan ai. Cell Res. 2022 Jan;32(1):72-88. doi: 10.1038/s41422-021-00580-z. Epub 2021 Oct 26. Cell Res. 2022. PMID: 34702947 Free PMC article.
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