Charton J - Search Results

1

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Picon S, Boulahjar R, Hoguet V, Baron M, Duplan I, Vallez E, Hennuyer N, Dumont J, Touche V, Dorchies E, Lasalle M, Descat A, Piveteau C, Biela A, Chaput L, Villoutreix BO, Lipka E, Sevin E, Culot M, Gosselet F, Lestavel S, Roussel P, Deprez-Poulain R, Leroux F, Staels B, Deprez B, Tailleux A, Charton J. Picon S, et al. Among authors: charton j. J Med Chem. 2023 Sep 14;66(17):11732-11760. doi: 10.1021/acs.jmedchem.2c01881. Epub 2023 Aug 28. J Med Chem. 2023. PMID: 37639383

2

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.

Flipo M, Beghyn T, Charton J, Leroux VA, Deprez BP, Deprez-Poulain RF. Flipo M, et al. Among authors: charton j. Bioorg Med Chem. 2007 Jan 1;15(1):63-76. doi: 10.1016/j.bmc.2006.10.010. Epub 2006 Oct 12. Bioorg Med Chem. 2007. PMID: 17070058

3

Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds.

Charton J, Charruault L, Deprez-Poulain R, Deprez B. Charton J, et al. Comb Chem High Throughput Screen. 2008 May;11(4):294-303. doi: 10.2174/138620708784246013. Comb Chem High Throughput Screen. 2008. PMID: 18473739

4

Synthesis of a 200-member library of squaric acid N-hydroxylamide amides.

Charton J, Leroux F, Delaroche S, Landry V, Déprez BP, Déprez-Poulain RF. Charton J, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):4968-71. doi: 10.1016/j.bmcl.2008.08.025. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18760922

5

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.

Charton J, Deprez-Poulain R, Hennuyer N, Tailleux A, Staels B, Deprez B. Charton J, et al. Bioorg Med Chem Lett. 2009 Jan 15;19(2):489-92. doi: 10.1016/j.bmcl.2008.11.040. Epub 2008 Nov 18. Bioorg Med Chem Lett. 2009. PMID: 19058965 Free article.

6

Enantioseparation of chiral benzimidazole derivatives by electrokinetic chromatography using sulfated cyclodextrins.

Lipka E, Charton J, Vaccher MP, Folly-Klan M, Bonte JP, Vaccher C. Lipka E, et al. Among authors: charton j. J Sep Sci. 2009 Jun;32(11):1907-15. doi: 10.1002/jssc.200800713. J Sep Sci. 2009. PMID: 19479770

7

Hydroxamates: relationships between structure and plasma stability.

Flipo M, Charton J, Hocine A, Dassonneville S, Deprez B, Deprez-Poulain R. Flipo M, et al. Among authors: charton j. J Med Chem. 2009 Nov 12;52(21):6790-802. doi: 10.1021/jm900648x. J Med Chem. 2009. PMID: 19821586

8

Determination of pKa values of benzimidazole derivatives from mobility obtained by capillary electrophoresis.

Lipka E, Folly-Klan M, Charton J, Vaccher MP, Bonte JP, Vaccher C. Lipka E, et al. Among authors: charton j. J Pharm Biomed Anal. 2010 Dec 15;53(5):1267-71. doi: 10.1016/j.jpba.2010.07.023. Epub 2010 Jul 27. J Pharm Biomed Anal. 2010. PMID: 20719448

9

Drug to genome to drug: discovery of new antiplasmodial compounds.

Beghyn TB, Charton J, Leroux F, Laconde G, Bourin A, Cos P, Maes L, Deprez B. Beghyn TB, et al. Among authors: charton j. J Med Chem. 2011 May 12;54(9):3222-40. doi: 10.1021/jm1014617. Epub 2011 Apr 19. J Med Chem. 2011. PMID: 21504142

10

Drug-to-genome-to-drug, step 2: reversing selectivity in a series of antiplasmodial compounds.

Beghyn TB, Charton J, Leroux F, Henninot A, Reboule I, Cos P, Maes L, Deprez B. Beghyn TB, et al. Among authors: charton j. J Med Chem. 2012 Feb 9;55(3):1274-86. doi: 10.1021/jm201422e. Epub 2012 Jan 24. J Med Chem. 2012. PMID: 22204607

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