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Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18.
Nature. 2017.
PMID: 29045389
Free PMC article.
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma.
Ruiz EJ, Pinto-Fernandez A, Turnbull AP, Lan L, Charlton TM, Scott HC, Damianou A, Vere G, Riising EM, Da Costa C, Krajewski WW, Guerin D, Kearns JD, Ioannidis S, Katz M, McKinnon C, O'Connell J, Moncaut N, Rosewell I, Nye E, Jones N, Heride C, Gersch M, Wu M, Dinsmore CJ, Hammonds TR, Kim S, Komander D, Urbe S, Clague MJ, Kessler BM, Behrens A.
Ruiz EJ, et al. Among authors: charlton tm.
Elife. 2021 Oct 12;10:e71596. doi: 10.7554/eLife.71596.
Elife. 2021.
PMID: 34636321
Free PMC article.
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FPR1 is the plague receptor on host immune cells.
Osei-Owusu P, Charlton TM, Kim HK, Missiakas D, Schneewind O.
Osei-Owusu P, et al. Among authors: charlton tm.
Nature. 2019 Oct;574(7776):57-62. doi: 10.1038/s41586-019-1570-z. Epub 2019 Sep 18.
Nature. 2019.
PMID: 31534221
Free PMC article.
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Glutathionylation of Yersinia pestis LcrV and Its Effects on Plague Pathogenesis.
Mitchell A, Tam C, Elli D, Charlton T, Osei-Owusu P, Fazlollahi F, Faull KF, Schneewind O.
Mitchell A, et al.
mBio. 2017 May 16;8(3):e00646-17. doi: 10.1128/mBio.00646-17.
mBio. 2017.
PMID: 28512097
Free PMC article.
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Quantitative Lipoproteomics in Clostridium difficile Reveals a Role for Lipoproteins in Sporulation.
Charlton TM, Kovacs-Simon A, Michell SL, Fairweather NF, Tate EW.
Charlton TM, et al.
Chem Biol. 2015 Nov 19;22(11):1562-1573. doi: 10.1016/j.chembiol.2015.10.006. Epub 2015 Nov 12.
Chem Biol. 2015.
PMID: 26584780
Free article.
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