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hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.
Osei-Amponsa V, Chandravanshi M, Lu X, Magidson V, Das S, Andresson T, Dyba M, Sabbasani VR, Swenson RE, Fromont C, Shrestha B, Zhao Y, Clapp ME, Chari R, Walters KJ. Osei-Amponsa V, et al. Among authors: chari r. Mol Cell. 2024 Feb 1;84(3):522-537.e8. doi: 10.1016/j.molcel.2023.11.035. Epub 2023 Dec 26. Mol Cell. 2024. PMID: 38151017
Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation.
Hartford CCR, Shrestha RL, Pongor L, Zhao Y, Chen X, Fromont C, Chaudhary R, Li XL, Pasterczyk KR, Kumar R, Muys BR, Tsitsipatis D, Chari R, Gorospe M, Aladjem MI, Khan J, Basrai MA, Grammatikakis I, Lal A. Hartford CCR, et al. Among authors: chari r. Mol Cell Biol. 2022 Dec 15;42(12):e0028922. doi: 10.1128/mcb.00289-22. Epub 2022 Nov 7. Mol Cell Biol. 2022. PMID: 36342127 Free PMC article.
An engineered cell line with a hRpn1-attached handle to isolate proteasomes.
Negi H, Osei-Amponsa V, Ibrahim B, Evans CN, Sullenberger C, Loncarek J, Chari R, Walters KJ. Negi H, et al. Among authors: chari r. J Biol Chem. 2023 Aug;299(8):104948. doi: 10.1016/j.jbc.2023.104948. Epub 2023 Jun 22. J Biol Chem. 2023. PMID: 37354974 Free PMC article.
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Nigam N, Bernard B, Sevilla S, Kim S, Dar MS, Tsai D, Robbins Y, Burkitt K, Sievers C, Allen CT, Bennett RL, Tettey TT, Carter B, Rinaldi L, Lingen MW, Sater H, Edmondson EF, Moshiri A, Saeed A, Cheng H, Luo X, Brennan K, Koparde V, Chen C, Das S, Andresson T, Abdelmaksoud A, Murali M, Sakata S, Takeuchi K, Chari R, Nakamura Y, Uppaluri R, Sunwoo JB, Van Waes C, Licht JD, Hager GL, Saloura V. Nigam N, et al. Among authors: chari r. Cell Rep. 2023 Jul 25;42(7):112823. doi: 10.1016/j.celrep.2023.112823. Epub 2023 Jul 17. Cell Rep. 2023. PMID: 37463106 Free PMC article.
Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants.
Sahu S, Sullivan TL, Mitrophanov AY, Galloux M, Nousome D, Southon E, Caylor D, Mishra AP, Evans CN, Clapp ME, Burkett S, Malys T, Chari R, Biswas K, Sharan SK. Sahu S, et al. Among authors: chari r. PLoS Genet. 2023 Sep 15;19(9):e1010940. doi: 10.1371/journal.pgen.1010940. eCollection 2023 Sep. PLoS Genet. 2023. PMID: 37713444 Free PMC article.
Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B.
Muys BR, Shrestha RL, Anastasakis DG, Pongor L, Li XL, Grammatikakis I, Polash A, Chari R, Gorospe M, Harris CC, Aladjem MI, Basrai MA, Hafner M, Lal A. Muys BR, et al. Among authors: chari r. Cell Rep. 2023 Mar 28;42(3):112260. doi: 10.1016/j.celrep.2023.112260. Epub 2023 Mar 15. Cell Rep. 2023. PMID: 36924503 Free PMC article.
Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer.
Sievers C, Craveiro M, Friedman J, Robbins Y, Yang X, Bai K, Nguyen A, Redman JM, Chari R, Soon-Shiong P, Schlom J, Gulley J, Allen CT. Sievers C, et al. Among authors: chari r. Cancer Cell. 2023 May 8;41(5):887-902.e5. doi: 10.1016/j.ccell.2023.03.014. Epub 2023 Apr 13. Cancer Cell. 2023. PMID: 37059104 Free PMC article.
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin.
Ruf B, Bruhns M, Babaei S, Kedei N, Ma L, Revsine M, Benmebarek MR, Ma C, Heinrich B, Subramanyam V, Qi J, Wabitsch S, Green BL, Bauer KC, Myojin Y, Greten LT, McCallen JD, Huang P, Trehan R, Wang X, Nur A, Murphy Soika DQ, Pouzolles M, Evans CN, Chari R, Kleiner DE, Telford W, Dadkhah K, Ruchinskas A, Stovroff MK, Kang J, Oza K, Ruchirawat M, Kroemer A, Wang XW, Claassen M, Korangy F, Greten TF. Ruf B, et al. Among authors: chari r. Cell. 2023 Aug 17;186(17):3686-3705.e32. doi: 10.1016/j.cell.2023.07.026. Cell. 2023. PMID: 37595566
358 results