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Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene.
Alomairi J, Molitor AM, Sadouni N, Hussain S, Torres M, Saadi W, Dao LTM, Charbonnier G, Santiago-Algarra D, Andrau JC, Puthier D, Sexton T, Spicuglia S. Alomairi J, et al. Among authors: charbonnier g. PLoS One. 2020 May 26;15(5):e0233191. doi: 10.1371/journal.pone.0233191. eCollection 2020. PLoS One. 2020. PMID: 32453736 Free PMC article.
Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.
Goudarzi A, Zhang D, Huang H, Barral S, Kwon OK, Qi S, Tang Z, Buchou T, Vitte AL, He T, Cheng Z, Montellier E, Gaucher J, Curtet S, Debernardi A, Charbonnier G, Puthier D, Petosa C, Panne D, Rousseaux S, Roeder RG, Zhao Y, Khochbin S. Goudarzi A, et al. Among authors: charbonnier g. Mol Cell. 2016 Apr 21;62(2):169-180. doi: 10.1016/j.molcel.2016.03.014. Mol Cell. 2016. PMID: 27105113 Free PMC article.
Genome-wide characterization of mammalian promoters with distal enhancer functions.
Dao LTM, Galindo-Albarrán AO, Castro-Mondragon JA, Andrieu-Soler C, Medina-Rivera A, Souaid C, Charbonnier G, Griffon A, Vanhille L, Stephen T, Alomairi J, Martin D, Torres M, Fernandez N, Soler E, van Helden J, Puthier D, Spicuglia S. Dao LTM, et al. Among authors: charbonnier g. Nat Genet. 2017 Jul;49(7):1073-1081. doi: 10.1038/ng.3884. Epub 2017 Jun 5. Nat Genet. 2017. PMID: 28581502
Explore, edit and leverage genomic annotations using Python GTF toolkit.
Lopez F, Charbonnier G, Kermezli Y, Belhocine M, Ferré Q, Zweig N, Aribi M, Gonzalez A, Spicuglia S, Puthier D. Lopez F, et al. Among authors: charbonnier g. Bioinformatics. 2019 Sep 15;35(18):3487-3488. doi: 10.1093/bioinformatics/btz116. Bioinformatics. 2019. PMID: 30768152
RNA-Guided Genomic Localization of H2A.L.2 Histone Variant.
Hoghoughi N, Barral S, Curtet S, Chuffart F, Charbonnier G, Puthier D, Buchou T, Rousseaux S, Khochbin S. Hoghoughi N, et al. Among authors: charbonnier g. Cells. 2020 Feb 18;9(2):474. doi: 10.3390/cells9020474. Cells. 2020. PMID: 32085641 Free PMC article.
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.
Cieslak A, Charbonnier G, Tesio M, Mathieu EL, Belhocine M, Touzart A, Smith C, Hypolite G, Andrieu GP, Martens JHA, Janssen-Megens E, Gut M, Gut I, Boissel N, Petit A, Puthier D, Macintyre E, Stunnenberg HG, Spicuglia S, Asnafi V. Cieslak A, et al. Among authors: charbonnier g. J Exp Med. 2020 Sep 7;217(9):e20192360. doi: 10.1084/jem.20192360. J Exp Med. 2020. PMID: 32667968 Free PMC article.
Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation.
Maqbool MA, Pioger L, El Aabidine AZ, Karasu N, Molitor AM, Dao LTM, Charbonnier G, van Laethem F, Fenouil R, Koch F, Lacaud G, Gut I, Gut M, Amigorena S, Joffre O, Sexton T, Spicuglia S, Andrau JC. Maqbool MA, et al. Among authors: charbonnier g. Cell Rep. 2020 Aug 18;32(7):108048. doi: 10.1016/j.celrep.2020.108048. Cell Rep. 2020. PMID: 32814051 Free article.
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.
Andrieu GP, Kohn M, Simonin M, Smith CL, Cieslak A, Dourthe MÉ, Charbonnier G, Graux C, Huguet F, Lhéritier V, Dombret H, Spicuglia S, Rousselot P, Boissel N, Asnafi V. Andrieu GP, et al. Among authors: charbonnier g. Blood. 2021 Nov 11;138(19):1855-1869. doi: 10.1182/blood.2020010081. Blood. 2021. PMID: 34125178 Free PMC article. Clinical Trial.
Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes.
Belhocine M, Simonin M, Abad Flores JD, Cieslak A, Manosalva I, Pradel L, Smith C, Mathieu EL, Charbonnier G, Martens JHA, Stunnenberg HG, Maqbool MA, Mikulasova A, Russell LJ, Rico D, Puthier D, Ferrier P, Asnafi V, Spicuglia S. Belhocine M, et al. Among authors: charbonnier g. Genome Res. 2022 Jul;32(7):1328-1342. doi: 10.1101/gr.266924.120. Epub 2021 Jun 23. Genome Res. 2022. PMID: 34162697 Free PMC article.
71 results