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Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel J, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: charabati m. bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574196. doi: 10.1101/2024.01.04.574196. bioRxiv. 2024. PMID: 38260616 Free PMC article. Updated. Preprint.
Interleukin-26, preferentially produced by TH17 lymphocytes, regulates CNS barrier function.
Broux B, Zandee S, Gowing E, Charabati M, Lécuyer MA, Tastet O, Hachehouche L, Bourbonnière L, Ouimet JP, Lemaitre F, Larouche S, Cayrol R, Bouthillier A, Moumdjian R, Lahav B, Poirier J, Duquette P, Arbour N, Peelen E, Prat A. Broux B, et al. Among authors: charabati m. Neurol Neuroimmunol Neuroinflamm. 2020 Aug 11;7(6):e870. doi: 10.1212/NXI.0000000000000870. Print 2020 Nov. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32788322 Free PMC article.
DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation.
Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, Lahav B, Moumdjian R, Bouthillier A, Girard M, Duquette P, Cayrol R, Peelen E, Quintana FJ, Antel JP, Flügel A, Larochelle C, Arbour N, Zandee S, Prat A. Charabati M, et al. Sci Transl Med. 2022 Jan 5;14(626):eabj0473. doi: 10.1126/scitranslmed.abj0473. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985970
Identification of astrocyte regulators by nucleic acid cytometry.
Clark IC, Wheeler MA, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, Rone JM, Giovannoni F, Charabati M, Akl CF, Aleman DM, Zandee SEJ, Prat A, Douek DC, Boritz EA, Quintana FJ, Abate AR. Clark IC, et al. Among authors: charabati m. Nature. 2023 Feb;614(7947):326-333. doi: 10.1038/s41586-022-05613-0. Epub 2023 Jan 4. Nature. 2023. PMID: 36599367 Free PMC article.
Droplet-based forward genetic screening of astrocyte-microglia cross-talk.
Wheeler MA, Clark IC, Lee HG, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ. Wheeler MA, et al. Among authors: charabati m. Science. 2023 Mar 10;379(6636):1023-1030. doi: 10.1126/science.abq4822. Epub 2023 Mar 9. Science. 2023. PMID: 36893254 Free PMC article.
31 results