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Copper(I)-Catalyzed Nitrile-Addition/N-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6H-indolo[3,2-c]quinolin-6-ones as Potent Topoisomerase-I Inhibitors.
Hsueh WY, Lee YE, Huang MS, Lai CH, Gao YS, Lin JC, Chen YF, Chang CL, Chou SY, Chen SF, Lu YY, Chang LH, Lin SF, Lin YH, Hsu PC, Wei WY, Huang YC, Kao YF, Teng LW, Liu HH, Chen YC, Yuan TT, Chan YW, Huang PH, Chao YT, Huang SY, Jian BH, Huang HY, Yang SC, Lo TH, Huang GR, Wang SY, Lin HS, Chuang SH, Huang JJ. Hsueh WY, et al. Among authors: chang lh, chang cl. J Med Chem. 2021 Feb 11;64(3):1435-1453. doi: 10.1021/acs.jmedchem.0c00727. Epub 2021 Jan 25. J Med Chem. 2021. PMID: 33492141
Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.
Chuang SH, Lee YE, Huang LYL, Chen CK, Lai CL, Lin YH, Yang JY, Yang SC, Chang LH, Chen CH, Liu CW, Lin HS, Lee YR, Huang KP, Fu KC, Jen HM, Lai JY, Jian PS, Wang YC, Hsueh WY, Tsai PY, Hong WH, Chang CC, Wu DZ, Wu J, Chen MH, Yu KM, Chern CY, Chang JM, Lau JYN, Huang JJ. Chuang SH, et al. Among authors: chang jm, chang cc, chang lh. Eur J Med Chem. 2020 Apr 1;191:112118. doi: 10.1016/j.ejmech.2020.112118. Epub 2020 Feb 7. Eur J Med Chem. 2020. PMID: 32113126
A Man With Tender Mass Over Proximal Tibia.
Chang LH, Tsai TY, Lin CH, Chau SW. Chang LH, et al. Ann Emerg Med. 2024 Jan;83(1):72-73. doi: 10.1016/j.annemergmed.2023.08.001. Ann Emerg Med. 2024. PMID: 38105101 No abstract available.
Phenotype plasticity and altered sensitivity to chemotherapeutic agents in aggressive prostate cancer cells.
Paxson AI, Chang LH, Gard JMC, Harryman WL, Nelson CS, Salmon SB, Marr KD, Wachsmuth LM, Ramanathan A, Ran J, Kapoor A, Marugan JJ, Henderson MJ, Sanchez TW, Cress AE. Paxson AI, et al. Among authors: chang lh. Front Cell Dev Biol. 2023 Nov 16;11:1285372. doi: 10.3389/fcell.2023.1285372. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38046670 Free PMC article.
245 results