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2,103 results

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Circular ecDNA promotes accessible chromatin and high oncogene expression.
Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, Coruh C, Abnousi A, Houston J, Ye Z, Hu R, Yu M, Kim H, Law JA, Verhaak RGW, Hu M, Furnari FB, Chang HY, Ren B, Bafna V, Mischel PS. Wu S, et al. Among authors: chang hy. Nature. 2019 Nov;575(7784):699-703. doi: 10.1038/s41586-019-1763-5. Epub 2019 Nov 20. Nature. 2019. PMID: 31748743 Free PMC article.
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. Michishita E, et al. Among authors: chang hy. Nature. 2008 Mar 27;452(7186):492-6. doi: 10.1038/nature06736. Epub 2008 Mar 12. Nature. 2008. PMID: 18337721 Free PMC article.
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY. Gupta RA, et al. Among authors: chang hy. Nature. 2010 Apr 15;464(7291):1071-6. doi: 10.1038/nature08975. Nature. 2010. PMID: 20393566 Free PMC article.
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.
Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. Wang KC, et al. Among authors: chang hy. Nature. 2011 Apr 7;472(7341):120-4. doi: 10.1038/nature09819. Epub 2011 Mar 20. Nature. 2011. PMID: 21423168 Free PMC article.
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY. Hung T, et al. Among authors: chang hy. Nat Genet. 2011 Jun 5;43(7):621-9. doi: 10.1038/ng.848. Nat Genet. 2011. PMID: 21642992 Free PMC article.
Understanding the transcriptome through RNA structure.
Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Wan Y, et al. Among authors: chang hy. Nat Rev Genet. 2011 Aug 18;12(9):641-55. doi: 10.1038/nrg3049. Nat Rev Genet. 2011. PMID: 21850044 Free PMC article. Review.
Control of somatic tissue differentiation by the long non-coding RNA TINCR.
Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, Aiyer S, Raj A, Rinn JL, Chang HY, Khavari PA. Kretz M, et al. Among authors: chang hy. Nature. 2013 Jan 10;493(7431):231-5. doi: 10.1038/nature11661. Epub 2012 Dec 2. Nature. 2013. PMID: 23201690 Free PMC article.
2,103 results