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The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. McQuattie-Pimentel AC, et al. Among authors: chandel ns. J Clin Invest. 2021 Feb 15;131(4):e140299. doi: 10.1172/JCI140299. J Clin Invest. 2021. PMID: 33586677 Free PMC article.
Inhibition of cytochrome-c oxidase activity during prolonged hypoxia.
Chandel N, Budinger GR, Kemp RA, Schumacker PT. Chandel N, et al. Am J Physiol. 1995 Jun;268(6 Pt 1):L918-25. doi: 10.1152/ajplung.1995.268.6.L918. Am J Physiol. 1995. PMID: 7611433
However, rat hepatocytes demonstrate a reversible suppression of respiration and an increase in NAD(P)H concentration during prolonged (2-24 h), but not acute hypoxia [P. T. Schumacker, N. Chandel, and A. G. N. Augusti. Am. J. Physiol. 265 (Lung Cell. Mol. ...By contrast, …
However, rat hepatocytes demonstrate a reversible suppression of respiration and an increase in NAD(P)H concentration during prolonged (2-24 …
Stretching the lung and programmed cell death.
Chandel NS, Sznajder JI. Chandel NS, et al. Am J Physiol Lung Cell Mol Physiol. 2000 Dec;279(6):L1003-4. doi: 10.1152/ajplung.2000.279.6.L1003. Am J Physiol Lung Cell Mol Physiol. 2000. PMID: 11076790 Free article. No abstract available.
Hypoxia sensitizes cells to nitric oxide-induced apoptosis.
Lee VY, McClintock DS, Santore MT, Budinger GR, Chandel NS. Lee VY, et al. Among authors: chandel ns. J Biol Chem. 2002 May 3;277(18):16067-74. doi: 10.1074/jbc.M111177200. Epub 2002 Feb 22. J Biol Chem. 2002. PMID: 11861645 Free article.
315 results