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Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
Guo M, Chan THM, Zhou Q, An O, Li Y, Song Y, Tan ZH, Ng VHE, Peramangalam PS, Tan ZQ, Cao X, Iwanaga E, Matsuoka M, Ooi MGM, Jen WY, Koh LP, Chan E, Tan LK, Goh Y, Wang W, Koh BTH, Chun CM, Fullwood MJ, Chng WJ, Osato M, Pulikkan JA, Yang H, Chen L, Tenen DG. Guo M, et al. Among authors: chan thm. Blood. 2023 Jun 22;141(25):3078-3090. doi: 10.1182/blood.2022015830. Blood. 2023. PMID: 36796022
Compound in-cis JAK2 mutant polycythemia vera manifesting as first-onset transient ischemic attack with erythrocytosis and an attenuated JAK2 V617F mutant signal on a quantitative DD-PCR assay.
Ng IKS, Lee PL, Ng LJ, Chua RP, Ng YA, Lee CK, Tan JG, Chan THM, Yan B, Prasad V. Ng IKS, et al. Among authors: chan thm. Int J Lab Hematol. 2023 Apr;45(2):e28-e31. doi: 10.1111/ijlh.13979. Epub 2022 Oct 7. Int J Lab Hematol. 2023. PMID: 36205319 No abstract available.
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Ho JS, Di Tullio F, Schwarz M, Low D, Incarnato D, Gay F, Tabaglio T, Zhang J, Wollmann H, Chen L, An O, Chan THM, Hall Hickman A, Zheng S, Roudko V, Chen S, Karz A, Ahmed M, He HH, Greenbaum BD, Oliviero S, Serresi M, Gargiulo G, Mann KM, Hernando E, Mulholland D, Marazzi I, Wee DKB, Guccione E. Ho JS, et al. Among authors: chan thm. Elife. 2021 Jun 2;10:e59654. doi: 10.7554/eLife.59654. Elife. 2021. PMID: 34075878 Free PMC article.
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.
Tay DJT, Song Y, Peng B, Toh TB, Hooi L, Toh DK, Hong H, Tang SJ, Han J, Gan WL, Chan THM, Krishna MS, Patil KM, Maraswami M, Loh TP, Dan YY, Zhou L, Bonney GK, Chow PK, Chen G, Chow EK, Le MTN, Chen L. Tay DJT, et al. Among authors: chan thm. Mol Ther. 2021 Nov 3;29(11):3258-3273. doi: 10.1016/j.ymthe.2021.05.008. Epub 2021 May 8. Mol Ther. 2021. PMID: 33974998 Free PMC article.
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Liu BH, Jobichen C, Chia CSB, Chan THM, Tang JP, Chung TXY, Li J, Poulsen A, Hung AW, Koh-Stenta X, Tan YS, Verma CS, Tan HK, Wu CS, Li F, Hill J, Joy J, Yang H, Chai L, Sivaraman J, Tenen DG. Liu BH, et al. Among authors: chan thm. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7119-E7128. doi: 10.1073/pnas.1801253115. Epub 2018 Jul 5. Proc Natl Acad Sci U S A. 2018. PMID: 29976840 Free PMC article.
34 results