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P21-activated kinase 1 (PAK1)-mediated cytoskeleton rearrangement promotes SARS-CoV-2 entry and ACE2 autophagic degradation.
Liu M, Lu B, Li Y, Yuan S, Zhuang Z, Li G, Wang D, Ma L, Zhu J, Zhao J, Chan CC, Poon VK, Chik KK, Zhao Z, Xian H, Zhao J, Zhao J, Chan JF, Zhang Y. Liu M, et al. Among authors: chan jf, chan cc. Signal Transduct Target Ther. 2023 Oct 9;8(1):385. doi: 10.1038/s41392-023-01631-0. Signal Transduct Target Ther. 2023. PMID: 37806990 Free PMC article.
Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis.
Zhou J, Chu H, Li C, Wong BH, Cheng ZS, Poon VK, Sun T, Lau CC, Wong KK, Chan JY, Chan JF, To KK, Chan KH, Zheng BJ, Yuen KY. Zhou J, et al. Among authors: chan jf, chan kh, chan jy. J Infect Dis. 2014 May 1;209(9):1331-42. doi: 10.1093/infdis/jit504. Epub 2013 Sep 24. J Infect Dis. 2014. PMID: 24065148 Free PMC article.
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.
Chan JF, Yip CC, Tsang JO, Tee KM, Cai JP, Chik KK, Zhu Z, Chan CC, Choi GK, Sridhar S, Zhang AJ, Lu G, Chiu K, Lo AC, Tsao SW, Kok KH, Jin DY, Chan KH, Yuen KY. Chan JF, et al. Among authors: chan kh, chan cc. Emerg Microbes Infect. 2016 Aug 24;5(8):e93. doi: 10.1038/emi.2016.99. Emerg Microbes Infect. 2016. PMID: 27553173 Free PMC article.
Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons.
Chan JF, Zhang AJ, Chan CC, Yip CC, Mak WW, Zhu H, Poon VK, Tee KM, Zhu Z, Cai JP, Tsang JO, Chik KK, Yin F, Chan KH, Kok KH, Jin DY, Au-Yeung RK, Yuen KY. Chan JF, et al. Among authors: chan kh, chan cc. EBioMedicine. 2016 Dec;14:112-122. doi: 10.1016/j.ebiom.2016.11.017. Epub 2016 Nov 12. EBioMedicine. 2016. PMID: 27884655 Free PMC article.
Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus.
Chan JF, Yip CC, Tee KM, Zhu Z, Tsang JO, Chik KK, Tsang TG, Chan CC, Poon VK, Sridhar S, Yin F, Hung IF, Chau SK, Zhang AJ, Chan KH, Yuen KY. Chan JF, et al. Among authors: chan kh, chan cc. Trop Med Int Health. 2017 May;22(5):594-603. doi: 10.1111/tmi.12857. Epub 2017 Mar 16. Trop Med Int Health. 2017. PMID: 28214373 Free article.
Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo.
Yuan S, Chan JF, den-Haan H, Chik KK, Zhang AJ, Chan CC, Poon VK, Yip CC, Mak WW, Zhu Z, Zou Z, Tee KM, Cai JP, Chan KH, de la Peña J, Pérez-Sánchez H, Cerón-Carrasco JP, Yuen KY. Yuan S, et al. Among authors: chan jf, chan kh, chan cc. Antiviral Res. 2017 Sep;145:33-43. doi: 10.1016/j.antiviral.2017.07.007. Epub 2017 Jul 14. Antiviral Res. 2017. PMID: 28712942
381 results