Chakravarti A - Search Results

1

Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth.

Cheng C, Ru P, Geng F, Liu J, Yoo JY, Wu X, Cheng X, Euthine V, Hu P, Guo JY, Lefai E, Kaur B, Nohturfft A, Ma J, Chakravarti A, Guo D. Cheng C, et al. Among authors: chakravarti a. Cancer Cell. 2015 Nov 9;28(5):569-581. doi: 10.1016/j.ccell.2015.09.021. Cancer Cell. 2015. PMID: 26555173 Free PMC article.

2

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.

Geng F, Cheng X, Wu X, Yoo JY, Cheng C, Guo JY, Mo X, Ru P, Hurwitz B, Kim SH, Otero J, Puduvalli V, Lefai E, Ma J, Nakano I, Horbinski C, Kaur B, Chakravarti A, Guo D. Geng F, et al. Among authors: chakravarti a. Clin Cancer Res. 2016 Nov 1;22(21):5337-5348. doi: 10.1158/1078-0432.CCR-15-2973. Epub 2016 Jun 8. Clin Cancer Res. 2016. PMID: 27281560 Free PMC article.

3

Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth.

Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D. Ru P, et al. Among authors: chakravarti a. Cell Rep. 2016 Aug 9;16(6):1527-1535. doi: 10.1016/j.celrep.2016.07.017. Epub 2016 Jul 28. Cell Rep. 2016. PMID: 27477273 Free PMC article.

4

Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth.

Cheng C, Geng F, Li Z, Zhong Y, Wang H, Cheng X, Zhao Y, Mo X, Horbinski C, Duan W, Chakravarti A, Cheng X, Guo D. Cheng C, et al. Among authors: chakravarti a. Nat Metab. 2022 May;4(5):575-588. doi: 10.1038/s42255-022-00568-y. Epub 2022 May 9. Nat Metab. 2022. PMID: 35534729 Free PMC article.

5

Targeting SREBP-1-driven lipid metabolism to treat cancer.

Guo D, Bell EH, Mischel P, Chakravarti A. Guo D, et al. Among authors: chakravarti a. Curr Pharm Des. 2014;20(15):2619-26. doi: 10.2174/13816128113199990486. Curr Pharm Des. 2014. PMID: 23859617 Free PMC article. Review.

6

Tumor metabolism of malignant gliomas.

Ru P, Williams TM, Chakravarti A, Guo D. Ru P, et al. Among authors: chakravarti a. Cancers (Basel). 2013 Nov 8;5(4):1469-84. doi: 10.3390/cancers5041469. Cancers (Basel). 2013. PMID: 24217114 Free PMC article.

7

Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth.

Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D. Ru P, et al. Among authors: chakravarti a. Cell Rep. 2017 Jan 24;18(4):1076-1077. doi: 10.1016/j.celrep.2017.01.016. Cell Rep. 2017. PMID: 28122233 Free article. No abstract available.

8

Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress.

Cheng X, Geng F, Pan M, Wu X, Zhong Y, Wang C, Tian Z, Cheng C, Zhang R, Puduvalli V, Horbinski C, Mo X, Han X, Chakravarti A, Guo D. Cheng X, et al. Among authors: chakravarti a. Cell Metab. 2020 Aug 4;32(2):229-242.e8. doi: 10.1016/j.cmet.2020.06.002. Epub 2020 Jun 18. Cell Metab. 2020. PMID: 32559414 Free PMC article.

9

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.

Guo D, Reinitz F, Youssef M, Hong C, Nathanson D, Akhavan D, Kuga D, Amzajerdi AN, Soto H, Zhu S, Babic I, Tanaka K, Dang J, Iwanami A, Gini B, Dejesus J, Lisiero DD, Huang TT, Prins RM, Wen PY, Robins HI, Prados MD, Deangelis LM, Mellinghoff IK, Mehta MP, James CD, Chakravarti A, Cloughesy TF, Tontonoz P, Mischel PS. Guo D, et al. Among authors: chakravarti a. Cancer Discov. 2011 Oct;1(5):442-56. doi: 10.1158/2159-8290.CD-11-0102. Epub 2011 Sep 15. Cancer Discov. 2011. PMID: 22059152 Free PMC article.

10

Lipid Droplets Maintain Energy Homeostasis and Glioblastoma Growth via Autophagic Release of Stored Fatty Acids.

Wu X, Geng F, Cheng X, Guo Q, Zhong Y, Cloughesy TF, Yong WH, Chakravarti A, Guo D. Wu X, et al. Among authors: chakravarti a. iScience. 2020 Sep 17;23(10):101569. doi: 10.1016/j.isci.2020.101569. eCollection 2020 Oct 23. iScience. 2020. PMID: 33083736 Free PMC article.

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