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NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors.
Ford K, Hanley CJ, Mellone M, Szyndralewiez C, Heitz F, Wiesel P, Wood O, Machado M, Lopez MA, Ganesan AP, Wang C, Chakravarthy A, Fenton TR, King EV, Vijayanand P, Ottensmeier CH, Al-Shamkhani A, Savelyeva N, Thomas GJ. Ford K, et al. Among authors: chakravarthy a. Cancer Res. 2020 May 1;80(9):1846-1860. doi: 10.1158/0008-5472.CAN-19-3158. Epub 2020 Mar 2. Cancer Res. 2020. PMID: 32122909 Free PMC article.
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.
Feber A, Worth DC, Chakravarthy A, de Winter P, Shah K, Arya M, Saqib M, Nigam R, Malone PR, Tan WS, Rodney S, Freeman A, Jameson C, Wilson GA, Powles T, Beck S, Fenton T, Sharp TV, Muneer A, Kelly JD. Feber A, et al. Among authors: chakravarthy a. Cancer Res. 2016 Aug 15;76(16):4720-4727. doi: 10.1158/0008-5472.CAN-15-3134. Epub 2016 Jun 20. Cancer Res. 2016. PMID: 27325650 Free PMC article.
Pan-cancer deconvolution of tumour composition using DNA methylation.
Chakravarthy A, Furness A, Joshi K, Ghorani E, Ford K, Ward MJ, King EV, Lechner M, Marafioti T, Quezada SA, Thomas GJ, Feber A, Fenton TR. Chakravarthy A, et al. Nat Commun. 2018 Aug 13;9(1):3220. doi: 10.1038/s41467-018-05570-1. Nat Commun. 2018. PMID: 30104673 Free PMC article.
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Chakravarthy A, Reddin I, Henderson S, Dong C, Kirkwood N, Jeyakumar M, Rodriguez DR, Martinez NG, McDermott J, Su X, Egawa N, Fjeldbo CS, Skingen VE, Lyng H, Halle MK, Krakstad C, Soleiman A, Sprung S, Lechner M, Ellis PJI, Wass M, Michaelis M, Fiegl H, Salvesen H, Thomas GJ, Doorbar J, Chester K, Feber A, Fenton TR. Chakravarthy A, et al. Nat Commun. 2022 Oct 7;13(1):5818. doi: 10.1038/s41467-022-33544-x. Nat Commun. 2022. PMID: 36207323 Free PMC article.
Frequent HPV-independent p16/INK4A overexpression in head and neck cancer.
Lechner M, Chakravarthy AR, Walter V, Masterson L, Feber A, Jay A, Weinberger PM, McIndoe RA, Forde CT, Chester K, Kalavrezos N, O'Flynn P, Forster M, Jones TM, Vaz FM, Hayes DN, Fenton TR. Lechner M, et al. Among authors: chakravarthy ar. Oral Oncol. 2018 Aug;83:32-37. doi: 10.1016/j.oraloncology.2018.06.006. Epub 2018 Jun 9. Oral Oncol. 2018. PMID: 30098776
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S. Lechner M, et al. Among authors: chakravarthy ar. Genome Med. 2013 Feb 5;5(2):15. doi: 10.1186/gm419. eCollection 2013. Genome Med. 2013. PMID: 23419152 Free PMC article.
148 results