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Peroxisome proliferator-activated receptors (PPAR) downregulate the expression of pro-inflammatory molecules in an experimental model of myocardial infarction.
Ibarra-Lara Mde L, Sánchez-Aguilar M, Soria E, Torres-Narváez JC, Del Valle-Mondragón L, Cervantes-Pérez LG, Pérez-Severiano F, Ramírez-Ortega Mdel C, Pastelín-Hernández G, Oidor-Chan VH, Sánchez-Mendoza A. Ibarra-Lara Mde L, et al. Can J Physiol Pharmacol. 2016 Jun;94(6):634-42. doi: 10.1139/cjpp-2015-0356. Epub 2016 Jan 17. Can J Physiol Pharmacol. 2016. PMID: 27050838
Clofibrate PPARα activation reduces oxidative stress and improves ultrastructure and ventricular hemodynamics in no-flow myocardial ischemia.
Ibarra-Lara L, Hong E, Soria-Castro E, Torres-Narváez JC, Pérez-Severiano F, Del Valle-Mondragón L, Cervantes-Pérez LG, Ramírez-Ortega M, Pastelín-Hernández GS, Sánchez-Mendoza A. Ibarra-Lara L, et al. J Cardiovasc Pharmacol. 2012 Oct;60(4):323-34. doi: 10.1097/FJC.0b013e31826216ed. J Cardiovasc Pharmacol. 2012. PMID: 22691880
PPARalpha stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner.
Ibarra-Lara L, Cervantes-Pérez LG, Pérez-Severiano F, Del Valle L, Rubio-Ruíz E, Soria-Castro E, Pastelín-Hernández GS, Sánchez-Aguilar M, Martínez-Lazcano JC, Sánchez-Mendoza A. Ibarra-Lara L, et al. Eur J Pharmacol. 2010 Feb 10;627(1-3):185-93. doi: 10.1016/j.ejphar.2009.10.039. Epub 2009 Oct 24. Eur J Pharmacol. 2010. PMID: 19857485
PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System.
Ibarra-Lara L, Sánchez-Aguilar M, Hong E, del Valle-Mondragón L, Soria-Castro E, Pérez-Severiano F, Torres-Narváez JC, Ramírez-Ortega M, Pastelín-Hernández GS, Cervantes-Pérez LG, Sánchez-Mendoza A. Ibarra-Lara L, et al. J Cardiovasc Pharmacol. 2015 May;65(5):430-7. doi: 10.1097/FJC.0000000000000186. J Cardiovasc Pharmacol. 2015. PMID: 25658458
Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Ibarra-Lara L, Del Valle-Mondragón L, Soria-Castro E, Torres-Narváez JC, Pérez-Severiano F, Sánchez-Aguilar M, Ramírez-Ortega M, Cervantes-Pérez LG, Pastelín-Hernández GS, Oidor-Chan VH, Zarco-Olvera G, Sánchez-Mendoza A. Ibarra-Lara L, et al. Among authors: cervantes perez lg. Pharmacol Rep. 2016 Aug;68(4):692-702. doi: 10.1016/j.pharep.2016.03.002. Epub 2016 Mar 21. Pharmacol Rep. 2016. PMID: 27110876
Clofibrate Treatment Decreases Inflammation and Reverses Myocardial Infarction-Induced Remodelation in a Rodent Experimental Model.
Ibarra-Lara L, Sánchez-Aguilar M, Soria-Castro E, Vargas-Barrón J, Roldán FJ, Pavón N, Torres-Narváez JC, Cervantes-Pérez LG, Pastelín-Hernández G, Sánchez-Mendoza A. Ibarra-Lara L, et al. Among authors: cervantes perez lg. Molecules. 2019 Jan 12;24(2):270. doi: 10.3390/molecules24020270. Molecules. 2019. PMID: 30642049 Free PMC article.
Clofibrate improves myocardial ischemia-induced damage through regulation of renin-angiotensin system and favours a pro-vasodilator profile in left ventricle.
Ibarra-Lara L, Sánchez-Aguilar M, Del Valle-Mondragón L, Soria-Castro E, Cervantes-Pérez LG, Pastelín-Hernández G, Sánchez-Mendoza A. Ibarra-Lara L, et al. Among authors: cervantes perez lg. J Pharmacol Sci. 2020 Dec;144(4):218-228. doi: 10.1016/j.jphs.2020.09.005. Epub 2020 Sep 18. J Pharmacol Sci. 2020. PMID: 33070841 Free article.
Fenofibrate Protects Cardiomyocytes from Hypoxia/Reperfusion- and High Glucose-Induced Detrimental Effects.
Cortes-Lopez F, Sanchez-Mendoza A, Centurion D, Cervantes-Perez LG, Castrejon-Tellez V, Del Valle-Mondragon L, Soria-Castro E, Ramirez V, Sanchez-Lopez A, Pastelin-Hernandez G, Garcia-Niño WR, Sanchez-Aguilar M, Ibarra-Lara L. Cortes-Lopez F, et al. Among authors: cervantes perez lg. PPAR Res. 2021 Jan 9;2021:8895376. doi: 10.1155/2021/8895376. eCollection 2021. PPAR Res. 2021. PMID: 33505452 Free PMC article.
Hyperglycemic levels in early stage of diabetic nephropathy affect differentially renal expression of claudins-2 and -5 by oxidative stress.
Rosas-Martínez L, Rodríguez-Muñoz R, Namorado-Tonix MDC, Missirlis F, Del Valle-Mondragón L, Sánchez-Mendoza A, Reyes-Sánchez JL, Cervantes-Pérez LG. Rosas-Martínez L, et al. Among authors: cervantes perez lg. Life Sci. 2021 Mar 1;268:119003. doi: 10.1016/j.lfs.2020.119003. Epub 2021 Jan 5. Life Sci. 2021. PMID: 33417957 Free article.
19 results