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Estrogen and progesterone decrease let-7f microRNA expression and increase IL-23/IL-23 receptor signaling and IL-17A production in patients with severe asthma.
Newcomb DC, Cephus JY, Boswell MG, Fahrenholz JM, Langley EW, Feldman AS, Zhou W, Dulek DE, Goleniewska K, Woodward KB, Sevin CM, Hamilton RG, Kolls JK, Peebles RS Jr. Newcomb DC, et al. Among authors: cephus jy. J Allergy Clin Immunol. 2015 Oct;136(4):1025-34.e11. doi: 10.1016/j.jaci.2015.05.046. Epub 2015 Aug 1. J Allergy Clin Immunol. 2015. PMID: 26242299 Free PMC article. Clinical Trial.
Testosterone Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation.
Cephus JY, Stier MT, Fuseini H, Yung JA, Toki S, Bloodworth MH, Zhou W, Goleniewska K, Zhang J, Garon SL, Hamilton RG, Poloshukin VV, Boyd KL, Peebles RS Jr, Newcomb DC. Cephus JY, et al. Cell Rep. 2017 Nov 28;21(9):2487-2499. doi: 10.1016/j.celrep.2017.10.110. Cell Rep. 2017. PMID: 29186686 Free PMC article.
Prostaglandin I2 signaling licenses Treg suppressive function and prevents pathogenic reprogramming.
Norlander AE, Bloodworth MH, Toki S, Zhang J, Zhou W, Boyd K, Polosukhin VV, Cephus JY, Ceneviva ZJ, Gandhi VD, Chowdhury NU, Charbonnier LM, Rogers LM, Wang J, Aronoff DM, Bastarache L, Newcomb DC, Chatila TA, Peebles RS Jr. Norlander AE, et al. Among authors: cephus jy. J Clin Invest. 2021 Apr 1;131(7):e140690. doi: 10.1172/JCI140690. J Clin Invest. 2021. PMID: 33529171 Free PMC article.
Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation.
Gandhi VD, Cephus JY, Norlander AE, Chowdhury NU, Zhang J, Ceneviva ZJ, Tannous E, Polosukhin VV, Putz ND, Wickersham N, Singh A, Ware LB, Bastarache JA, Shaver CM, Chu HW, Peebles RS Jr, Newcomb DC. Gandhi VD, et al. Among authors: cephus jy. J Clin Invest. 2022 Feb 15;132(4):e153397. doi: 10.1172/JCI153397. J Clin Invest. 2022. PMID: 35025767 Free PMC article.
18 results