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Benefit of Early versus Deferred Antiretroviral Therapy on Progression of Liver Fibrosis among People with HIV in the START Randomized Trial.
Dharan NJ, Neuhaus J, Rockstroh JK, Peters L, Gordin F, Arenas-Pinto A, Emerson C, Marks K, Hidalgo J, Sarmento-Castro R, Stephan C, Kumarasamy N, Emery S, Matthews GV; INSIGHT START Study Group. Dharan NJ, et al. Hepatology. 2019 Mar;69(3):1135-1150. doi: 10.1002/hep.30296. Epub 2019 Feb 19. Hepatology. 2019. PMID: 30298608 Free PMC article. Clinical Trial.
Social stress shortens lifespan in mice.
Razzoli M, Nyuyki-Dufe K, Gurney A, Erickson C, McCallum J, Spielman N, Marzullo M, Patricelli J, Kurata M, Pope EA, Touma C, Palme R, Largaespada DA, Allison DB, Bartolomucci A. Razzoli M, et al. Aging Cell. 2018 Aug;17(4):e12778. doi: 10.1111/acel.12778. Epub 2018 May 28. Aging Cell. 2018. PMID: 29806171 Free PMC article.
In conclusion, we present here the first rodent model to study and mechanistically dissect the impact of chronic stress on lifespan and disease of aging. These data highlight a conserved role for social stress and low social status on shortening lifespan and increasing the …
In conclusion, we present here the first rodent model to study and mechanistically dissect the impact of chronic stress on lifespan and dise …