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Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.
Needham EJ, Ren AL, Digby RJ, Norton EJ, Ebrahimi S, Outtrim JG, Chatfield DA, Manktelow AE, Leibowitz MM, Newcombe VFJ, Doffinger R, Barcenas-Morales G, Fonseca C, Taussig MJ, Burnstein RM, Samanta RJ, Dunai C, Sithole N, Ashton NJ, Zetterberg H, Gisslén M, Edén A, Marklund E, Openshaw PJM, Dunning J, Griffiths MJ, Cavanagh J, Breen G, Irani SR, Elmer A, Kingston N, Summers C, Bradley JR, Taams LS, Michael BD, Bullmore ET, Smith KGC, Lyons PA, Coles AJ, Menon DK; Cambridge NeuroCOVID Group; CITIID-NIHR COVID-19 BioResource Collaboration; Cambridge NIHR Clinical Research Facility. Needham EJ, et al. Among authors: cavanagh j. Brain. 2022 Nov 21;145(11):4097-4107. doi: 10.1093/brain/awac321. Brain. 2022. PMID: 36065116 Free PMC article.
Treatment-resistant depression and peripheral C-reactive protein.
Chamberlain SR, Cavanagh J, de Boer P, Mondelli V, Jones DNC, Drevets WC, Cowen PJ, Harrison NA, Pointon L, Pariante CM, Bullmore ET. Chamberlain SR, et al. Among authors: cavanagh j. Br J Psychiatry. 2019 Jan;214(1):11-19. doi: 10.1192/bjp.2018.66. Epub 2018 May 16. Br J Psychiatry. 2019. PMID: 29764522 Free PMC article.
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium; Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH. Mancuso R, et al. Brain. 2019 Oct 1;142(10):3243-3264. doi: 10.1093/brain/awz241. Brain. 2019. PMID: 31504240 Free PMC article.
Childhood trauma, HPA axis activity and antidepressant response in patients with depression.
Nikkheslat N, McLaughlin AP, Hastings C, Zajkowska Z, Nettis MA, Mariani N, Enache D, Lombardo G, Pointon L, Cowen PJ, Cavanagh J, Harrison NA, Bullmore ET; NIMA Consortium; Pariante CM, Mondelli V. Nikkheslat N, et al. Among authors: cavanagh j. Brain Behav Immun. 2020 Jul;87:229-237. doi: 10.1016/j.bbi.2019.11.024. Epub 2019 Nov 30. Brain Behav Immun. 2020. PMID: 31794798 Free PMC article.
Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression.
Aruldass AR, Kitzbichler MG, Morgan SE, Lim S, Lynall ME, Turner L, Vertes P; Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA); Cavanagh J, Cowen P, Pariante CM, Harrison NA, Bullmore ET. Aruldass AR, et al. Among authors: cavanagh j. Brain Behav Immun. 2021 Nov;98:299-309. doi: 10.1016/j.bbi.2021.08.226. Epub 2021 Aug 25. Brain Behav Immun. 2021. PMID: 34450247 Free article.
Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks.
Kitzbichler MG, Aruldass AR, Barker GJ, Wood TC, Dowell NG, Hurley SA, McLean J, Correia M, Clarke C, Pointon L, Cavanagh J, Cowen P, Pariante C, Cercignani M; Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium; Bullmore ET, Harrison NA. Kitzbichler MG, et al. Among authors: cavanagh j. Mol Psychiatry. 2021 Dec;26(12):7346-7354. doi: 10.1038/s41380-021-01272-1. Epub 2021 Sep 17. Mol Psychiatry. 2021. PMID: 34535766 Free PMC article.
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC, Daines L, Baillie JK, Brown JS, Chalder T, De Soyza A, Diar Bakerly N, Easom N, Geddes JR, Greening NJ, Hart N, Heaney LG, Heller S, Howard L, Hurst JR, Jacob J, Jenkins RG, Jolley C, Kerr S, Kon OM, Lewis K, Lord JM, McCann GP, Neubauer S, Openshaw PJM, Parekh D, Pfeffer P, Rahman NM, Raman B, Richardson M, Rowland M, Semple MG, Shah AM, Singh SJ, Sheikh A, Thomas D, Toshner M, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Wain LV, Brightling CE; PHOSP-COVID Collaborative Group. Evans RA, et al. Lancet Respir Med. 2021 Nov;9(11):1275-1287. doi: 10.1016/S2213-2600(21)00383-0. Epub 2021 Oct 7. Lancet Respir Med. 2021. PMID: 34627560 Free PMC article.
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: cavanagh j. Nat Commun. 2023 Dec 22;14(1):8487. doi: 10.1038/s41467-023-42320-4. Nat Commun. 2023. PMID: 38135686 Free PMC article.
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: cavanagh j. Nat Commun. 2024 Apr 4;15(1):2918. doi: 10.1038/s41467-024-47320-6. Nat Commun. 2024. PMID: 38575615 Free PMC article. No abstract available.
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression.
Lynall ME, Turner L, Bhatti J, Cavanagh J, de Boer P, Mondelli V, Jones D, Drevets WC, Cowen P, Harrison NA, Pariante CM, Pointon L, Clatworthy MR, Bullmore E; Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium. Lynall ME, et al. Among authors: cavanagh j. Biol Psychiatry. 2020 Jul 15;88(2):185-196. doi: 10.1016/j.biopsych.2019.11.017. Epub 2019 Dec 2. Biol Psychiatry. 2020. PMID: 32000983
695 results