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Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes.
Waibel M, Wentworth JM, So M, Couper JJ, Cameron FJ, MacIsaac RJ, Atlas G, Gorelik A, Litwak S, Sanz-Villanueva L, Trivedi P, Ahmed S, Martin FJ, Doyle ME, Harbison JE, Hall C, Krishnamurthy B, Colman PG, Harrison LC, Thomas HE, Kay TWH; BANDIT Study Group. Waibel M, et al. N Engl J Med. 2023 Dec 7;389(23):2140-2150. doi: 10.1056/NEJMoa2306691. N Engl J Med. 2023. PMID: 38055252 Clinical Trial.
Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor.
Ge T, Phung AL, Jhala G, Trivedi P, Principe N, De George DJ, Pappas EG, Litwak S, Sanz-Villanueva L, Catterall T, Fynch S, Boon L, Kay TW, Chee J, Krishnamurthy B, Thomas HE. Ge T, et al. Among authors: catterall t. Clin Transl Immunology. 2022 Oct 30;11(11):e1425. doi: 10.1002/cti2.1425. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36325490 Free PMC article.
The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice.
Ge T, Jhala G, Fynch S, Akazawa S, Litwak S, Pappas EG, Catterall T, Vakil I, Long AJ, Olson LM, Krishnamurthy B, Kay TW, Thomas HE. Ge T, et al. Among authors: catterall t. Front Immunol. 2020 Dec 4;11:588543. doi: 10.3389/fimmu.2020.588543. eCollection 2020. Front Immunol. 2020. PMID: 33343569 Free PMC article.
16 results