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Substituted Purines as High-Affinity Histamine H3 Receptor Ligands.
Espinosa-Bustos C, Leitzbach L, Añazco T, Silva MJ, Campo AD, Castro-Alvarez A, Stark H, Salas CO. Espinosa-Bustos C, et al. Pharmaceuticals (Basel). 2022 May 4;15(5):573. doi: 10.3390/ph15050573. Pharmaceuticals (Basel). 2022. PMID: 35631399 Free PMC article.
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.
Bertrand J, Dostálová H, Kryštof V, Jorda R, Delgado T, Castro-Alvarez A, Mella J, Cabezas D, Faúndez M, Espinosa-Bustos C, Salas CO. Bertrand J, et al. Among authors: castro alvarez a. Pharmaceutics. 2022 Jun 17;14(6):1294. doi: 10.3390/pharmaceutics14061294. Pharmaceutics. 2022. PMID: 35745866 Free PMC article.
In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies.
Cabezas D, Mellado G, Espinoza N, Gárate JA, Morales C, Castro-Alvarez A, Matos MJ, Mellado M, Mella J. Cabezas D, et al. Among authors: castro alvarez a. J Biomol Struct Dyn. 2023;41(22):13250-13259. doi: 10.1080/07391102.2023.2172457. Epub 2023 Jan 30. J Biomol Struct Dyn. 2023. PMID: 36718094
20 results