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Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression.
Ruivo CF, Bastos N, Adem B, Batista I, Duraes C, Melo CA, Castaldo SA, Campos-Laborie F, Moutinho-Ribeiro P, Morão B, Costa-Pinto A, Silva S, Osorio H, Ciordia S, Costa JL, Goodrich D, Cavadas B, Pereira L, Kouzarides T, Macedo G, Maio R, Carneiro F, Cravo M, Kalluri R, Machado JC, Melo SA. Ruivo CF, et al. Among authors: castaldo sa. Gut. 2022 Jan 10;71(10):2043-68. doi: 10.1136/gutjnl-2021-324994. Online ahead of print. Gut. 2022. PMID: 35012996 Free PMC article.
Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.
Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, Verhulst S, Karras P, van Huffel L, Zender L, Marine JC, Roskams T, Johnson R, Aerts S, van Grunsven LA, Halder G. Moya IM, et al. Among authors: castaldo sa. Science. 2019 Nov 22;366(6468):1029-1034. doi: 10.1126/science.aaw9886. Science. 2019. PMID: 31754005
Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis.
Verboven E, Moya IM, Sansores-Garcia L, Xie J, Hillen H, Kowalczyk W, Vella G, Verhulst S, Castaldo SA, Algueró-Nadal A, Romanelli L, Mercader-Celma C, Souza NA, Soheily S, Van Huffel L, Van Brussel T, Lambrechts D, Roskams T, Lemaigre FP, Bergers G, van Grunsven LA, Halder G. Verboven E, et al. Among authors: castaldo sa. Gastroenterology. 2021 Feb;160(3):847-862. doi: 10.1053/j.gastro.2020.10.035. Epub 2020 Oct 28. Gastroenterology. 2021. PMID: 33127392 Free article.
The Tumorigenic Roles of the Cellular REDOX Regulatory Systems.
Castaldo SA, Freitas JR, Conchinha NV, Madureira PA. Castaldo SA, et al. Oxid Med Cell Longev. 2016;2016:8413032. doi: 10.1155/2016/8413032. Epub 2015 Nov 22. Oxid Med Cell Longev. 2016. PMID: 26682014 Free PMC article. Review.