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AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Trepte P, Secker C, Kostova S, Maseko SB, Choi SG, Blavier J, Minia I, Ramos ES, Cassonnet P, Golusik S, Zenkner M, Beetz S, Liebich MJ, Scharek N, Schütz A, Sperling M, Lisurek M, Wang Y, Spirohn K, Hao T, Calderwood MA, Hill DE, Landthaler M, Olivet J, Twizere JC, Vidal M, Wanker EE. Trepte P, et al. Among authors: cassonnet p. bioRxiv [Preprint]. 2023 Jun 14:2023.06.14.544560. doi: 10.1101/2023.06.14.544560. bioRxiv. 2023. PMID: 37398436 Free PMC article. Updated. Preprint.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Trepte P, Secker C, Olivet J, Blavier J, Kostova S, Maseko SB, Minia I, Silva Ramos E, Cassonnet P, Golusik S, Zenkner M, Beetz S, Liebich MJ, Scharek N, Schütz A, Sperling M, Lisurek M, Wang Y, Spirohn K, Hao T, Calderwood MA, Hill DE, Landthaler M, Choi SG, Twizere JC, Vidal M, Wanker EE. Trepte P, et al. Among authors: cassonnet p. Mol Syst Biol. 2024 Apr;20(4):428-457. doi: 10.1038/s44320-024-00019-8. Epub 2024 Mar 11. Mol Syst Biol. 2024. PMID: 38467836 Free PMC article.
A proteome-scale map of the SARS-CoV-2-human contactome.
Kim DK, Weller B, Lin CW, Sheykhkarimli D, Knapp JJ, Dugied G, Zanzoni A, Pons C, Tofaute MJ, Maseko SB, Spirohn K, Laval F, Lambourne L, Kishore N, Rayhan A, Sauer M, Young V, Halder H, la Rosa NM, Pogoutse O, Strobel A, Schwehn P, Li R, Rothballer ST, Altmann M, Cassonnet P, Coté AG, Vergara LE, Hazelwood I, Liu BB, Nguyen M, Pandiarajan R, Dohai B, Coloma PAR, Poirson J, Giuliana P, Willems L, Taipale M, Jacob Y, Hao T, Hill DE, Brun C, Twizere JC, Krappmann D, Heinig M, Falter C, Aloy P, Demeret C, Vidal M, Calderwood MA, Roth FP, Falter-Braun P. Kim DK, et al. Among authors: cassonnet p. Nat Biotechnol. 2023 Jan;41(1):140-149. doi: 10.1038/s41587-022-01475-z. Epub 2022 Oct 10. Nat Biotechnol. 2023. PMID: 36217029 Free PMC article.
The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection.
Schor S, Pu S, Nicolaescu V, Azari S, Kõivomägi M, Karim M, Cassonnet P, Saul S, Neveu G, Yueh A, Demeret C, Skotheim JM, Jacob Y, Randall G, Einav S. Schor S, et al. Among authors: cassonnet p. J Biol Chem. 2022 Jun;298(6):101956. doi: 10.1016/j.jbc.2022.101956. Epub 2022 Apr 20. J Biol Chem. 2022. PMID: 35452674 Free PMC article.
A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions.
Kim DK, Knapp JJ, Kuang D, Chawla A, Cassonnet P, Lee H, Sheykhkarimli D, Samavarchi-Tehrani P, Abdouni H, Rayhan A, Li R, Pogoutse O, Coyaud É, van der Werf S, Demeret C, Gingras AC, Taipale M, Raught B, Jacob Y, Roth FP. Kim DK, et al. Among authors: cassonnet p. G3 (Bethesda). 2020 Sep 2;10(9):3399-3402. doi: 10.1534/g3.120.401554. G3 (Bethesda). 2020. PMID: 32763951 Free PMC article.
Maximizing binary interactome mapping with a minimal number of assays.
Choi SG, Olivet J, Cassonnet P, Vidalain PO, Luck K, Lambourne L, Spirohn K, Lemmens I, Dos Santos M, Demeret C, Jones L, Rangarajan S, Bian W, Coutant EP, Janin YL, van der Werf S, Trepte P, Wanker EE, De Las Rivas J, Tavernier J, Twizere JC, Hao T, Hill DE, Vidal M, Calderwood MA, Jacob Y. Choi SG, et al. Among authors: cassonnet p. Nat Commun. 2019 Aug 29;10(1):3907. doi: 10.1038/s41467-019-11809-2. Nat Commun. 2019. PMID: 31467278 Free PMC article.
The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome.
Bureau JF, Cassonnet P, Grange L, Dessapt J, Jones L, Demeret C, Sakuntabhai A, Jacob Y. Bureau JF, et al. Among authors: cassonnet p. Oncotarget. 2018 Feb 6;9(17):13102-13115. doi: 10.18632/oncotarget.24424. eCollection 2018 Mar 2. Oncotarget. 2018. PMID: 29568343 Free PMC article.
Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans.
Biquand E, Poirson J, Karim M, Declercq M, Malausse N, Cassonnet P, Barbezange C, Straub ML, Jones L, Munier S, Naffakh N, van der Werf S, Jacob Y, Masson M, Demeret C. Biquand E, et al. Among authors: cassonnet p. mSphere. 2017 Nov 22;2(6):e00330-17. doi: 10.1128/mSphere.00330-17. eCollection 2017 Nov-Dec. mSphere. 2017. PMID: 29202037 Free PMC article.
Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.
Dabo S, Maillard P, Collados Rodriguez M, Hansen MD, Mazouz S, Bigot DJ, Tible M, Janvier G, Helynck O, Cassonnet P, Jacob Y, Bellalou J, Gatignol A, Patel RC, Hugon J, Munier-Lehmann H, Meurs EF. Dabo S, et al. Among authors: cassonnet p. Sci Rep. 2017 Nov 23;7(1):16129. doi: 10.1038/s41598-017-16089-8. Sci Rep. 2017. PMID: 29170442 Free PMC article.
29 results