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Identification of Novel Neutralizing Monoclonal Antibodies against SARS-CoV-2 Spike Glycoprotein.
Bordoloi D, Xu Z, Ho M, Purwar M, Bhojnagarwala P, Cassel J, Giron LB, Walker S, Kulkarni AJ, Ruiz ET, Choi J, Zaidi FI, Wu Y, Wang S, Patel A, Ramos S, Smith T, Kulp D, Ugen KE, Srinivasan A, Abdel-Mohsen M, Humeau L, Weiner DB, Muthumani K. Bordoloi D, et al. Among authors: cassel j. ACS Pharmacol Transl Sci. 2021 Jul 29;4(4):1349-1361. doi: 10.1021/acsptsci.1c00058. eCollection 2021 Aug 13. ACS Pharmacol Transl Sci. 2021. PMID: 34396059 Free PMC article.
Retraction Note: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance.
Singh KS, Sharma R, Reddy PAN, Vonteddu P, Good M, Sundarrajan A, Choi H, Muthumani K, Kossenkov A, Goldman AR, Tang HY, Totrov M, Cassel J, Murphy ME, Somasundaram R, Herlyn M, Salvino JM, Dotiwala F. Singh KS, et al. Among authors: cassel j. Nature. 2021 Nov;599(7885):518. doi: 10.1038/s41586-021-03961-x. Nature. 2021. PMID: 34580487 Free PMC article. No abstract available.
Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers.
Bordoloi D, Kulkarni AJ, Adeniji OS, Pampena MB, Bhojnagarwala PS, Zhao S, Ionescu C, Perales-Puchalt A, Parzych EM, Zhu X, Ali AR, Cassel J, Zhang R, Betts MR, Abdel-Mohsen M, Weiner DB. Bordoloi D, et al. Among authors: cassel j. Sci Adv. 2023 Nov 3;9(44):eadh4379. doi: 10.1126/sciadv.adh4379. Epub 2023 Nov 1. Sci Adv. 2023. PMID: 37910620 Free PMC article.
IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance.
Singh KS, Sharma R, Reddy PAN, Vonteddu P, Good M, Sundarrajan A, Choi H, Muthumani K, Kossenkov A, Goldman AR, Tang HY, Totrov M, Cassel J, Murphy ME, Somasundaram R, Herlyn M, Salvino JM, Dotiwala F. Singh KS, et al. Among authors: cassel j. Nature. 2021 Jan;589(7843):597-602. doi: 10.1038/s41586-020-03074-x. Epub 2020 Dec 23. Nature. 2021. PMID: 33361818 Free PMC article. Retracted.
Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding.
Invernizzi L, Moyo P, Cassel J, Isaacs FJ, Salvino JM, Montaner LJ, Tietjen I, Maharaj V. Invernizzi L, et al. Among authors: cassel j. Anal Bioanal Chem. 2022 May;414(13):3971-3985. doi: 10.1007/s00216-022-04041-3. Epub 2022 Apr 14. Anal Bioanal Chem. 2022. PMID: 35419694 Free PMC article.
The Natural Stilbenoid (-)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants.
Tietjen I, Cassel J, Register ET, Zhou XY, Messick TE, Keeney F, Lu LD, Beattie KD, Rali T, Tebas P, Ertl HCJ, Salvino JM, Davis RA, Montaner LJ. Tietjen I, et al. Among authors: cassel j. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0077221. doi: 10.1128/AAC.00772-21. Epub 2021 Sep 20. Antimicrob Agents Chemother. 2021. PMID: 34543092 Free PMC article.
Metabolic control of BRISC-SHMT2 assembly regulates immune signalling.
Walden M, Tian L, Ross RL, Sykora UM, Byrne DP, Hesketh EL, Masandi SK, Cassel J, George R, Ault JR, El Oualid F, Pawłowski K, Salvino JM, Eyers PA, Ranson NA, Del Galdo F, Greenberg RA, Zeqiraj E. Walden M, et al. Among authors: cassel j. Nature. 2019 Jun;570(7760):194-199. doi: 10.1038/s41586-019-1232-1. Epub 2019 May 29. Nature. 2019. PMID: 31142841 Free PMC article.
448 results