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Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells.
Nat Cell Biol. 2022 Jan;24(1):10-23. doi: 10.1038/s41556-021-00809-4. Epub 2021 Dec 30.
Nat Cell Biol. 2022.
PMID: 34969962
Free PMC article.
Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung.
Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T.
Cassandras M, et al.
Nat Cell Biol. 2020 Nov;22(11):1295-1306. doi: 10.1038/s41556-020-00591-9. Epub 2020 Oct 12.
Nat Cell Biol. 2020.
PMID: 33046884
Free PMC article.
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Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype.
Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T.
Wang C, et al. Among authors: cassandras m.
J Clin Invest. 2018 Oct 1;128(10):4343-4358. doi: 10.1172/JCI99435. Epub 2018 Jul 12.
J Clin Invest. 2018.
PMID: 29999500
Free PMC article.
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The Role of Hedgehog Signaling in Adult Lung Regeneration and Maintenance.
Wang C, Cassandras M, Peng T.
Wang C, et al. Among authors: cassandras m.
J Dev Biol. 2019 Jul 9;7(3):14. doi: 10.3390/jdb7030014.
J Dev Biol. 2019.
PMID: 31323955
Free PMC article.
Review.
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Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung.
Reyes NS, Krasilnikov M, Allen NC, Lee JY, Hyams B, Zhou M, Ravishankar S, Cassandras M, Wang C, Khan I, Matatia P, Johmura Y, Molofsky A, Matthay M, Nakanishi M, Sheppard D, Campisi J, Peng T.
Reyes NS, et al. Among authors: cassandras m.
Science. 2022 Oct 14;378(6616):192-201. doi: 10.1126/science.abf3326. Epub 2022 Oct 13.
Science. 2022.
PMID: 36227993
Free PMC article.
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