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TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).
Abouyannis M, FitzGerald R, Ngama M, Mwangudzah H, Nyambura YK, Ngome S, Riako D, Babu L, Lewa F, Else L, Dily Penchala S, Orindi B, Mumba N, Kalama B, Ndungu FM, Adetifa I, Khoo S, Lalloo DG, Casewell NR, Hamaluba M. Abouyannis M, et al. Among authors: casewell nr. Wellcome Open Res. 2022 Mar 14;7:90. doi: 10.12688/wellcomeopenres.17682.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 35372700 Free PMC article.
Two snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing.
Menzies SK, Litschka-Koen T, Edge RJ, Alsolaiss J, Crittenden E, Hall SR, Westhorpe A, Thomas B, Murray J, Shongwe N, Padidar S, Lalloo DG, Casewell NR, Pons J, Harrison RA. Menzies SK, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2022 Sep 15;16(9):e0010496. doi: 10.1371/journal.pntd.0010496. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36108067 Free PMC article.
A global core outcome measurement set for snakebite clinical trials.
Abouyannis M, Esmail H, Hamaluba M, Ngama M, Mwangudzah H, Mumba N, Yeri BK, Mwalukore S, Alphan HJ, Aggarwal D, Alcoba G, Cammack N, Chippaux JP, Coldiron ME, Gutiérrez JM, Habib AG, Harrison RA, Isbister GK, Lavonas EJ, Martins D, Ribeiro I, Watson JA, Williams DJ, Casewell NR, Walker SA, Lalloo DG; Snakebite Global Core Outcome Set Study Group. Abouyannis M, et al. Among authors: casewell nr. Lancet Glob Health. 2023 Feb;11(2):e296-e300. doi: 10.1016/S2214-109X(22)00479-X. Lancet Glob Health. 2023. PMID: 36669810 Free article. Review.
Diagnostic characteristics of the 20-minute whole blood clotting test in detecting venom-induced consumptive coagulopathy following carpet viper envenoming.
Tianyi FL, Hamza M, Abubakar SB, Al Solaiss J, Trelfa A, Abdullahi HL, Iliyasu G, Mohammed N, Mohammed SA, Casewell NR, Harrison RA, Lalloo DG, Stienstra Y, Habib AG. Tianyi FL, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2023 Jun 26;17(6):e0011442. doi: 10.1371/journal.pntd.0011442. eCollection 2023 Jun. PLoS Negl Trop Dis. 2023. PMID: 37363905 Free PMC article.
Snakebite prevalence and risk factors in a nomadic population in Samburu County, Kenya: A community-based survey.
Tianyi FL, Oluoch GO, Otundo D, Ofwete R, Ngari C, Trelfa A, Ahmed S, Wang D, Smith M, Meta V, Casewell NR, Lalloo DG, Harrison RA, Stienstra Y. Tianyi FL, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2024 Jan 2;18(1):e0011678. doi: 10.1371/journal.pntd.0011678. eCollection 2024 Jan. PLoS Negl Trop Dis. 2024. PMID: 38165835 Free PMC article.
In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus.
Menzies SK, Clare RH, Xie C, Westhorpe A, Hall SR, Edge RJ, Alsolaiss J, Crittenden E, Marriott AE, Harrison RA, Kool J, Casewell NR. Menzies SK, et al. Among authors: casewell nr. Toxicon X. 2022 Mar 18;14:100118. doi: 10.1016/j.toxcx.2022.100118. eCollection 2022 Jun. Toxicon X. 2022. PMID: 35321116 Free PMC article.
147 results