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Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold.
Rong J, Mori W, Xia X, Schafroth MA, Zhao C, Van RS, Yamasaki T, Chen J, Xiao Z, Haider A, Ogasawara D, Hiraishi A, Shao T, Zhang Y, Chen Z, Pang F, Hu K, Xie L, Fujinaga M, Kumata K, Gou Y, Fang Y, Gu S, Wei H, Bao L, Xu H, Collier TL, Shao Y, Carson RE, Cravatt BF, Wang L, Zhang MR, Liang SH. Rong J, et al. Among authors: carson re. J Med Chem. 2021 Oct 14;64(19):14283-14298. doi: 10.1021/acs.jmedchem.1c00747. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34569803 Free PMC article.
Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies.
Bennacef I, Salinas CA, Bonasera TA, Gunn RN, Audrain H, Jakobsen S, Nabulsi N, Weinzimmer D, Carson RE, Huang Y, Holmes I, Micheli F, Heidbreder C, Gentile G, Rossi T, Laruelle M. Bennacef I, et al. Among authors: carson re. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5056-9. doi: 10.1016/j.bmcl.2009.07.055. Epub 2009 Jul 25. Bioorg Med Chem Lett. 2009. PMID: 19635669
Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer 11C-TASP699.
Naganawa M, Nabulsi NB, Matuskey D, Henry S, Ropchan J, Lin SF, Gao H, Pracitto R, Labaree D, Zhang MR, Suhara T, Nishino I, Sabia H, Ozaki S, Huang Y, Carson RE. Naganawa M, et al. Among authors: carson re. J Nucl Med. 2022 Apr;63(4):609-614. doi: 10.2967/jnumed.121.262430. Epub 2021 Aug 12. J Nucl Med. 2022. PMID: 34385336 Free article.
A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: synthesis and preclinical characterization of [18F]SDM-16.
Zheng C, Holden D, Zheng MQ, Pracitto R, Wilcox KC, Lindemann M, Felchner Z, Zhang L, Tong J, Fowles K, Finnema SJ, Nabulsi N, Carson RE, Huang Y, Cai Z. Zheng C, et al. Among authors: carson re. Eur J Nucl Med Mol Imaging. 2022 Apr;49(5):1482-1496. doi: 10.1007/s00259-021-05597-5. Epub 2021 Nov 11. Eur J Nucl Med Mol Imaging. 2022. PMID: 34761284 Free PMC article.
Characterization in nonhuman primates of (R)-[18F]OF-Me-NB1 and (S)-[18F]OF-Me-NB1 for imaging the GluN2B subunits of the NMDA receptor.
Zheng M, Ahmed H, Smart K, Xu Y, Holden D, Kapinos M, Felchner Z, Haider A, Tamagnan G, Carson RE, Huang Y, Ametamey SM. Zheng M, et al. Among authors: carson re. Eur J Nucl Med Mol Imaging. 2022 Jun;49(7):2153-2162. doi: 10.1007/s00259-022-05698-9. Epub 2022 Feb 2. Eur J Nucl Med Mol Imaging. 2022. PMID: 35107627 Free PMC article.
Comparison of three novel radiotracers for GluN2B-containing NMDA receptors in non-human primates: (R)-[11C]NR2B-Me, (R)-[18F]of-Me-NB1, and (S)-[18F]of-NB1.
Smart K, Zheng MQ, Ahmed H, Fang H, Xu Y, Cai L, Holden D, Kapinos M, Haider A, Felchner Z, Ropchan JR, Tamagnan G, Innis RB, Pike VW, Ametamey SM, Huang Y, Carson RE. Smart K, et al. Among authors: carson re. J Cereb Blood Flow Metab. 2022 Aug;42(8):1398-1409. doi: 10.1177/0271678X221084416. Epub 2022 Feb 25. J Cereb Blood Flow Metab. 2022. PMID: 35209743 Free PMC article.
Development of fluorine-18-labeled 5-HT1A antagonists.
Lang L, Jagoda E, Schmall B, Vuong BK, Adams HR, Nelson DL, Carson RE, Eckelman WC. Lang L, et al. Among authors: carson re. J Med Chem. 1999 May 6;42(9):1576-86. doi: 10.1021/jm980456f. J Med Chem. 1999. PMID: 10229627
608 results