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Tramadol and caffeine produce synergistic interactions on antinociception measured in a formalin model.
Pharmacol Biochem Behav. 2010 Dec;97(2):357-62. doi: 10.1016/j.pbb.2010.09.004. Epub 2010 Sep 15.
Pharmacol Biochem Behav. 2010.
PMID: 20837047
[Synergism of caffeine on antinociceptive effects of metamizole].
Díaz-Reval MI, Galván-Orozco R, López-Muñoz FJ, Carrillo-Munguía N.
Díaz-Reval MI, et al. Among authors: carrillo munguia n.
Cir Cir. 2008 May-Jun;76(3):241-6.
Cir Cir. 2008.
PMID: 18647558
Spanish.
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Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms.
Carrillo-Munguía N, González-Trujano ME, Huerta M, Trujillo X, Díaz-Reval MI.
Carrillo-Munguía N, et al.
Biomed Res Int. 2015;2015:686424. doi: 10.1155/2015/686424. Epub 2015 Jun 4.
Biomed Res Int. 2015.
PMID: 26146627
Free PMC article.
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