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Hexamethylene amiloride engages a novel reactive oxygen species- and lysosome-dependent programmed necrotic mechanism to selectively target breast cancer cells.
Rowson-Hodel AR, Berg AL, Wald JH, Hatakeyama J, VanderVorst K, Curiel DA, Leon LJ, Sweeney C, Carraway KL 3rd. Rowson-Hodel AR, et al. Among authors: carraway kl 3rd. Cancer Lett. 2016 May 28;375(1):62-72. doi: 10.1016/j.canlet.2016.02.042. Epub 2016 Mar 2. Cancer Lett. 2016. PMID: 26944316 Free PMC article.
The role of membrane mucin MUC4 in breast cancer metastasis.
Dreyer CA, VanderVorst K, Free S, Rowson-Hodel A, Carraway KL. Dreyer CA, et al. Among authors: carraway kl. Endocr Relat Cancer. 2021 Nov 24;29(1):R17-R32. doi: 10.1530/ERC-21-0083. Endocr Relat Cancer. 2021. PMID: 34726614 Free PMC article. Review.
The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies.
Berg AL, Rowson-Hodel A, Hu M, Keeling M, Wu H, VanderVorst K, Chen JJ, Hatakeyama J, Jilek J, Dreyer CA, Wheeler MR, Yu AM, Li Y, Carraway KL 3rd. Berg AL, et al. Among authors: carraway kl 3rd. Cancers (Basel). 2022 Feb 14;14(4):949. doi: 10.3390/cancers14040949. Cancers (Basel). 2022. PMID: 35205696 Free PMC article.
Leucine-rich repeat and immunoglobulin domain-containing protein-1 (Lrig1) negative regulatory action toward ErbB receptor tyrosine kinases is opposed by leucine-rich repeat and immunoglobulin domain-containing protein 3 (Lrig3).
Rafidi H, Mercado F 3rd, Astudillo M, Fry WH, Saldana M, Carraway KL 3rd, Sweeney C. Rafidi H, et al. Among authors: carraway kl 3rd. J Biol Chem. 2013 Jul 26;288(30):21593-605. doi: 10.1074/jbc.M113.486050. Epub 2013 May 30. J Biol Chem. 2013. PMID: 23723069 Free PMC article.
270 results