Carragher N - Search Results

1

MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity.

Peirsman A, Blondeel E, Ahmed T, Anckaert J, Audenaert D, Boterberg T, Buzas K, Carragher N, Castellani G, Castro F, Dangles-Marie V, Dawson J, De Tullio P, De Vlieghere E, Dedeyne S, Depypere H, Diosdi A, Dmitriev RI, Dolznig H, Fischer S, Gespach C, Goossens V, Heino J, Hendrix A, Horvath P, Kunz-Schughart LA, Maes S, Mangodt C, Mestdagh P, Michlíková S, Oliveira MJ, Pampaloni F, Piccinini F, Pinheiro C, Rahn J, Robbins SM, Siljamäki E, Steigemann P, Sys G, Takayama S, Tesei A, Tulkens J, Van Waeyenberge M, Vandesompele J, Wagemans G, Weindorfer C, Yigit N, Zablowsky N, Zanoni M, Blondeel P, De Wever O. Peirsman A, et al. Among authors: carragher n. Nat Methods. 2021 Nov;18(11):1294-1303. doi: 10.1038/s41592-021-01291-4. Epub 2021 Nov 1. Nat Methods. 2021. PMID: 34725485 Free PMC article.

2

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach.

Weiss JT, Dawson JC, Macleod KG, Rybski W, Fraser C, Torres-Sánchez C, Patton EE, Bradley M, Carragher NO, Unciti-Broceta A. Weiss JT, et al. Nat Commun. 2014;5:3277. doi: 10.1038/ncomms4277. Nat Commun. 2014. PMID: 24522696 Free PMC article.

3

Quantitative phenotypic and pathway profiling guides rational drug combination strategies.

Dawson JC, Carragher NO. Dawson JC, et al. Front Pharmacol. 2014 May 28;5:118. doi: 10.3389/fphar.2014.00118. eCollection 2014. Front Pharmacol. 2014. PMID: 24904421 Free PMC article. Review.

4

Development of the Theta Comparative Cell Scoring Method to Quantify Diverse Phenotypic Responses Between Distinct Cell Types.

Warchal SJ, Dawson JC, Carragher NO. Warchal SJ, et al. Assay Drug Dev Technol. 2016 Sep;14(7):395-406. doi: 10.1089/adt.2016.730. Assay Drug Dev Technol. 2016. PMID: 27552144 Free PMC article.

5

Screening out irrelevant cell-based models of disease.

Horvath P, Aulner N, Bickle M, Davies AM, Nery ED, Ebner D, Montoya MC, Östling P, Pietiäinen V, Price LS, Shorte SL, Turcatti G, von Schantz C, Carragher NO. Horvath P, et al. Among authors: carragher no. Nat Rev Drug Discov. 2016 Nov;15(11):751-769. doi: 10.1038/nrd.2016.175. Epub 2016 Sep 12. Nat Rev Drug Discov. 2016. PMID: 27616293 Review.

6

High-Dimensional Profiling: The Theta Comparative Cell Scoring Method.

Warchal SJ, Dawson JC, Carragher NO. Warchal SJ, et al. Methods Mol Biol. 2018;1787:171-181. doi: 10.1007/978-1-4939-7847-2_13. Methods Mol Biol. 2018. PMID: 29736718

7

Concerns, challenges and promises of high-content analysis of 3D cellular models.

Carragher N, Piccinini F, Tesei A, Trask OJ Jr, Bickle M, Horvath P. Carragher N, et al. Nat Rev Drug Discov. 2018 Aug;17(8):606. doi: 10.1038/nrd.2018.99. Epub 2018 Jul 6. Nat Rev Drug Discov. 2018. PMID: 29977053 No abstract available.

8

Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines.

Warchal SJ, Dawson JC, Carragher NO. Warchal SJ, et al. SLAS Discov. 2019 Mar;24(3):224-233. doi: 10.1177/2472555218820805. Epub 2019 Jan 29. SLAS Discov. 2019. PMID: 30694704 Free PMC article.

9

High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways.

Warchal SJ, Dawson JC, Shepherd E, Munro AF, Hughes RE, Makda A, Carragher NO. Warchal SJ, et al. Bioorg Med Chem. 2020 Jan 1;28(1):115209. doi: 10.1016/j.bmc.2019.115209. Epub 2019 Nov 9. Bioorg Med Chem. 2020. PMID: 31757681 Free PMC article.

10

Drug Screening Platforms and RPPA.

Dawson JC, Warchal SJ, Carragher NO. Dawson JC, et al. Adv Exp Med Biol. 2019;1188:203-226. doi: 10.1007/978-981-32-9755-5_11. Adv Exp Med Biol. 2019. PMID: 31820390 Review.

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