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Immunochemotherapy for visceral leishmaniasis: combinatorial action of Miltefosine plus LBSapMPL vaccine improves adaptative Th1 immune response with control of splenic parasitism in experimental hamster model.
Carvalho LM, Gusmão MR, Costa AFP, de Brito RCF, Aguiar-Soares RDO, Cardoso JMO, Reis AB, Carneiro CM, Roatt BM. Carvalho LM, et al. Among authors: cardoso jmo. Parasitology. 2022 Mar;149(3):371-379. doi: 10.1017/S0031182021001906. Epub 2021 Nov 2. Parasitology. 2022. PMID: 35264268 Free PMC article.
LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4⁺ and CD8⁺) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis.
Aguiar-Soares RD, Roatt BM, Ker HG, Moreira Nd, Mathias FA, Cardoso JM, Gontijo NF, Bruna-Romero O, Teixeira-Carvalho A, Martins-Filho OA, Corrêa-Oliveira R, Giunchetti RC, Reis AB. Aguiar-Soares RD, et al. Parasit Vectors. 2014 Feb 7;7:61. doi: 10.1186/1756-3305-7-61. Parasit Vectors. 2014. PMID: 24507702 Free PMC article.
A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden.
Roatt BM, Aguiar-Soares RD, Reis LE, Cardoso JM, Mathias FA, de Brito RC, da Silva SM, Gontijo NF, Ferreira SA, Valenzuela JG, Corrêa-Oliveira R, Giunchetti RC, Reis AB. Roatt BM, et al. Front Immunol. 2017 Mar 7;8:217. doi: 10.3389/fimmu.2017.00217. eCollection 2017. Front Immunol. 2017. PMID: 28321217 Free PMC article.
Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice.
Reis LES, Fortes de Brito RC, Cardoso JMO, Mathias FAS, Aguiar Soares RDO, Carneiro CM, de Abreu Vieira PM, Ramos GS, Frézard FJG, Roatt BM, Reis AB. Reis LES, et al. Among authors: cardoso jmo. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e00962-17. doi: 10.1128/AAC.00962-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28827416 Free PMC article.
Canine visceral leishmaniasis biomarkers and their employment in vaccines.
Giunchetti RC, Silveira P, Resende LA, Leite JC, Melo-Júnior OAO, Rodrigues-Alves ML, Costa LM, Lair DF, Chaves VR, Soares IDS, de Mendonça LZ, Lanna MF, Ribeiro HS, Maia-Gonçalves AA, Santos TAP, Roatt BM, Aguiar-Soares RDO, Vitoriano-Souza J, das Dores Moreira N, Mathias FAS, Cardoso JMO, Coura-Vital W, Galdino AS, Viana KF, Martins-Filho OA, Silveira-Lemos DD, Dutra WO, Reis AB. Giunchetti RC, et al. Among authors: cardoso jmo. Vet Parasitol. 2019 Jul;271:87-97. doi: 10.1016/j.vetpar.2019.05.006. Epub 2019 May 20. Vet Parasitol. 2019. PMID: 31303211 Review.
Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice.
De Brito RCF, Cardoso JMO, Reis LES, Mathias FAS, Aguiar-Soares RDO, Teixeira-Carvalho A, Roatt BM, Corrêa-Oliveira R, Ruiz JC, Resende DM, Reis AB. De Brito RCF, et al. Among authors: cardoso jmo. Vaccines (Basel). 2019 Oct 28;7(4):162. doi: 10.3390/vaccines7040162. Vaccines (Basel). 2019. PMID: 31661776 Free PMC article.
30 results