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A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
Brooks-Warburton J, Modos D, Sudhakar P, Madgwick M, Thomas JP, Bohar B, Fazekas D, Zoufir A, Kapuy O, Szalay-Beko M, Verstockt B, Hall LJ, Watson A, Tremelling M, Parkes M, Vermeire S, Bender A, Carding SR, Korcsmaros T. Brooks-Warburton J, et al. Among authors: carding sr. Nat Commun. 2022 Apr 28;13(1):2299. doi: 10.1038/s41467-022-29998-8. Nat Commun. 2022. PMID: 35484353 Free PMC article.
Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy.
Jones EJ, Matthews ZJ, Gul L, Sudhakar P, Treveil A, Divekar D, Buck J, Wrzesinski T, Jefferson M, Armstrong SD, Hall LJ, Watson AJM, Carding SR, Haerty W, Di Palma F, Mayer U, Powell PP, Hautefort I, Wileman T, Korcsmaros T. Jones EJ, et al. Among authors: carding sr. Dis Model Mech. 2019 Mar 18;12(3):dmm037069. doi: 10.1242/dmm.037069. Dis Model Mech. 2019. PMID: 30814064 Free PMC article.
Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell-type specific manner that are altered in inflammatory bowel disease.
Gul L, Modos D, Fonseca S, Madgwick M, Thomas JP, Sudhakar P, Booth C, Stentz R, Carding SR, Korcsmaros T. Gul L, et al. Among authors: carding sr. J Extracell Vesicles. 2022 Jan;11(1):e12189. doi: 10.1002/jev2.12189. J Extracell Vesicles. 2022. PMID: 35064769 Free PMC article.
The Proteome of Extracellular Vesicles Produced by the Human Gut Bacteria Bacteroides thetaiotaomicron In Vivo Is Influenced by Environmental and Host-Derived Factors.
Stentz R, Jones E, Juodeikis R, Wegmann U, Guirro M, Goldson AJ, Brion A, Booth C, Sudhakar P, Brown IR, Korcsmáros T, Carding SR. Stentz R, et al. Among authors: carding sr. Appl Environ Microbiol. 2022 Aug 23;88(16):e0053322. doi: 10.1128/aem.00533-22. Epub 2022 Aug 2. Appl Environ Microbiol. 2022. PMID: 35916501 Free PMC article.
The early-life gut microbiome and vaccine efficacy.
Jordan A, Carding SR, Hall LJ. Jordan A, et al. Among authors: carding sr. Lancet Microbe. 2022 Oct;3(10):e787-e794. doi: 10.1016/S2666-5247(22)00185-9. Epub 2022 Sep 8. Lancet Microbe. 2022. PMID: 36088916 Free article. Review.
188 results