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Safety and pharmacokinetics of oral and long-acting injectable cabotegravir or long-acting injectable rilpivirine in virologically suppressed adolescents with HIV (IMPAACT 2017/MOCHA): a phase 1/2, multicentre, open-label, non-comparative, dose-finding study.
Gaur AH, Capparelli EV, Calabrese K, Baltrusaitis K, Marzinke MA, McCoig C, Van Solingen-Ristea RM, Mathiba SR, Adeyeye A, Moye JH, Heckman B, Lowenthal ED, Ward S, Milligan R, Samson P, Best BM, Harrington CM, Ford SL, Huang J, Crauwels H, Vandermeulen K, Agwu AL, Smith-Anderson C, Camacho-Gonzalez A, Ounchanum P, Kneebone JL, Townley E, Bolton Moore C; IMPAACT 2017 Collaborators; IMPAACT 2017 Team. Gaur AH, et al. Among authors: capparelli ev. Lancet HIV. 2024 Apr;11(4):e211-e221. doi: 10.1016/S2352-3018(23)00300-4. Lancet HIV. 2024. PMID: 38538160 Clinical Trial.
Pharmacokinetics of Tenofovir Alafenamide With Boosted Protease Inhibitors in Pregnant and Postpartum Women Living With HIV: Results From IMPAACT P1026s.
Brooks KM, Pinilla M, Stek AM, Shapiro DE, Barr E, Febo IL, Paul ME, Deville JG, George K, Knowles K, Rungruengthanakit K, Browning R, Chakhtoura N, Capparelli EV, Mirochnick M, Best BM; IMPAACT P1026s Protocol Team. Brooks KM, et al. Among authors: capparelli ev. J Acquir Immune Defic Syndr. 2022 Jul 1;90(3):343-350. doi: 10.1097/QAI.0000000000002944. J Acquir Immune Defic Syndr. 2022. PMID: 35195573 Free PMC article.
Maraviroc Population Pharmacokinetics Within the First 6 Weeks of Life.
Liyanage M, Nikanjam M, McFadyen L, Vourvahis M, Rogg L, Moye J, Chadwick EG, Jean-Philippe P, Mirochnick M, Whitson K, Bradford S, Capparelli EV, Best BM. Liyanage M, et al. Among authors: capparelli ev. Pediatr Infect Dis J. 2022 Nov 1;41(11):885-890. doi: 10.1097/INF.0000000000003665. Epub 2022 Aug 9. Pediatr Infect Dis J. 2022. PMID: 35980827 Free PMC article.
Alteration in cytochrome P450 3A4 activity as measured by a urine cortisol assay in HIV-1-infected pregnant women and relationship to antiretroviral pharmacokinetics.
Aweeka FT, Hu C, Huang L, Best BM, Stek A, Lizak P, Burchett SK, Read JS, Watts H, Mirochnick M, Capparelli EV; International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) P1026s Protocol Team. Aweeka FT, et al. Among authors: capparelli ev. HIV Med. 2015 Mar;16(3):176-83. doi: 10.1111/hiv.12195. Epub 2014 Nov 18. HIV Med. 2015. PMID: 25407158 Free PMC article.
Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women.
Tran AH, Best BM, Stek A, Wang J, Capparelli EV, Burchett SK, Kreitchmann R, Rungruengthanakit K, George K, Cressey TR, Chakhtoura N, Smith E, Shapiro DE, Mirochnick M; IMPAACT P1026s Protocol Team. Tran AH, et al. Among authors: capparelli ev. J Acquir Immune Defic Syndr. 2016 Jul 1;72(3):289-96. doi: 10.1097/QAI.0000000000000968. J Acquir Immune Defic Syndr. 2016. PMID: 26918544 Free PMC article. Clinical Trial.
Rilpivirine Plasma and Cervicovaginal Concentrations in Women During Pregnancy and Postpartum.
Eke AC, Chakhtoura N, Kashuba A, Best BM, Sykes C, Wang J, Stek AM, Smith E, Calabrese S, Capparelli EV, Mirochnick M; IMPAACT P1026s Protocol Team. Eke AC, et al. Among authors: capparelli ev. J Acquir Immune Defic Syndr. 2018 Jul 1;78(3):308-313. doi: 10.1097/QAI.0000000000001677. J Acquir Immune Defic Syndr. 2018. PMID: 29528944 Free PMC article.
Association of Virologic Failure and Nonnucleoside Reverse Transcriptase Inhibitor Resistance Found in Antiretroviral-Naive Children Infected With Human Immunodeficiency Virus and Given Efavirenz-Based Treatment.
Higa N, Pelz A, Birch D, Beck IA, Sils T, Samson P, Bwakura-Dangarembizi M, Bolton-Moore C, Capparelli E, Chadwick E, Frenkel LM. Higa N, et al. J Pediatric Infect Dis Soc. 2020 Apr 30;9(2):261-264. doi: 10.1093/jpids/piz038. J Pediatric Infect Dis Soc. 2020. PMID: 31194860 Free PMC article.
Darunavir Pharmacokinetics With an Increased Dose During Pregnancy.
Eke AC, Stek AM, Wang J, Kreitchmann R, Shapiro DE, Smith E, Chakhtoura N, Capparelli EV, Mirochnick M, Best BM; IMPAACT P1026s Protocol Team. Eke AC, et al. Among authors: capparelli ev. J Acquir Immune Defic Syndr. 2020 Apr 1;83(4):373-380. doi: 10.1097/QAI.0000000000002261. J Acquir Immune Defic Syndr. 2020. PMID: 31923087 Free PMC article.
372 results