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GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
Quarta C, Stemmer K, Novikoff A, Yang B, Klingelhuber F, Harger A, Bakhti M, Bastidas-Ponce A, Baugé E, Campbell JE, Capozzi M, Clemmensen C, Collden G, Cota P, Douros J, Drucker DJ, DuBois B, Feuchtinger A, Garcia-Caceres C, Grandl G, Hennuyer N, Herzig S, Hofmann SM, Knerr PJ, Kulaj K, Lalloyer F, Lickert H, Liskiewicz A, Liskiewicz D, Maity G, Perez-Tilve D, Prakash S, Sanchez-Garrido MA, Zhang Q, Staels B, Krahmer N, DiMarchi RD, Tschöp MH, Finan B, Müller TD. Quarta C, et al. Among authors: capozzi m. Nat Metab. 2022 Aug;4(8):1071-1083. doi: 10.1038/s42255-022-00617-6. Epub 2022 Aug 22. Nat Metab. 2022. PMID: 35995995 Free PMC article.
Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction.
Ussher JR, Campbell JE, Mulvihill EE, Baggio LL, Bates HE, McLean BA, Gopal K, Capozzi M, Yusta B, Cao X, Ali S, Kim M, Kabir MG, Seino Y, Suzuki J, Drucker DJ. Ussher JR, et al. Among authors: capozzi m. Cell Metab. 2018 Feb 6;27(2):450-460.e6. doi: 10.1016/j.cmet.2017.11.003. Epub 2017 Dec 21. Cell Metab. 2018. PMID: 29275960 Free article.
β Cell tone is defined by proglucagon peptides through cAMP signaling.
Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. Capozzi ME, et al. JCI Insight. 2019 Mar 7;4(5):e126742. doi: 10.1172/jci.insight.126742. eCollection 2019 Mar 7. JCI Insight. 2019. PMID: 30720465 Free PMC article.
Glucagon lowers glycemia when β-cells are active.
Capozzi ME, Wait JB, Koech J, Gordon AN, Coch RW, Svendsen B, Finan B, D'Alessio DA, Campbell JE. Capozzi ME, et al. JCI Insight. 2019 Jul 23;5(16):e129954. doi: 10.1172/jci.insight.129954. JCI Insight. 2019. PMID: 31335319 Free PMC article.
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
Al Batran R, Gopal K, Capozzi ME, Chahade JJ, Saleme B, Tabatabaei-Dakhili SA, Greenwell AA, Niu J, Almutairi M, Byrne NJ, Masson G, Kim R, Eaton F, Mulvihill EE, Garneau L, Masters AR, Desta Z, Velázquez-Martínez CA, Aguer C, Crawford PA, Sutendra G, Campbell JE, Dyck JRB, Ussher JR. Al Batran R, et al. Among authors: capozzi me. Cell Metab. 2020 May 5;31(5):909-919.e8. doi: 10.1016/j.cmet.2020.03.017. Epub 2020 Apr 9. Cell Metab. 2020. PMID: 32275862 Free article.
183 results