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A kinase-cGAS cascade to synthesize a therapeutic STING activator.
Nature. 2022 Mar;603(7901):439-444. doi: 10.1038/s41586-022-04422-9. Epub 2022 Mar 16.
Nature. 2022.
PMID: 35296845
Design of an in vitro biocatalytic cascade for the manufacture of islatravir.
Huffman MA, Fryszkowska A, Alvizo O, Borra-Garske M, Campos KR, Canada KA, Devine PN, Duan D, Forstater JH, Grosser ST, Halsey HM, Hughes GJ, Jo J, Joyce LA, Kolev JN, Liang J, Maloney KM, Mann BF, Marshall NM, McLaughlin M, Moore JC, Murphy GS, Nawrat CC, Nazor J, Novick S, Patel NR, Rodriguez-Granillo A, Robaire SA, Sherer EC, Truppo MD, Whittaker AM, Verma D, Xiao L, Xu Y, Yang H.
Huffman MA, et al. Among authors: canada ka.
Science. 2019 Dec 6;366(6470):1255-1259. doi: 10.1126/science.aay8484.
Science. 2019.
PMID: 31806816
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A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Fryszkowska A, An C, Alvizo O, Banerjee G, Canada KA, Cao Y, DeMong D, Devine PN, Duan D, Elgart DM, Farasat I, Gauthier DR, Guidry EN, Jia X, Kong J, Kruse N, Lexa KW, Makarov AA, Mann BF, Milczek EM, Mitchell V, Nazor J, Neri C, Orr RK, Orth P, Phillips EM, Riggins JN, Schafer WA, Silverman SM, Strulson CA, Subramanian N, Voladri R, Yang H, Yang J, Yi X, Zhang X, Zhong W.
Fryszkowska A, et al. Among authors: canada ka.
Science. 2022 Jun 17;376(6599):1321-1327. doi: 10.1126/science.abn2009. Epub 2022 Jun 16.
Science. 2022.
PMID: 35709255
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Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations.
Brown ZZ, Mapelli C, Farasat I, Shoultz AV, Johnson SA, Orvieto F, Santoprete A, Bianchi E, McCracken AB, Chen K, Zhu X, Demma MJ, Lacey BM, Canada KA, Garbaccio RM, O'Neil J, Walji A.
Brown ZZ, et al. Among authors: canada ka.
J Org Chem. 2020 Feb 7;85(3):1466-1475. doi: 10.1021/acs.joc.9b02467. Epub 2019 Nov 25.
J Org Chem. 2020.
PMID: 31660743
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Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.
Ganesan R, Raymond EL, Mennerich D, Woska JR Jr, Caviness G, Grimaldi C, Ahlberg J, Perez R, Roberts S, Yang D, Jerath K, Truncali K, Frego L, Sepulveda E, Gupta P, Brown SE, Howell MD, Canada KA, Kroe-Barrett R, Fine JS, Singh S, Mbow ML.
Ganesan R, et al. Among authors: canada ka.
MAbs. 2017 Oct;9(7):1143-1154. doi: 10.1080/19420862.2017.1353853. Epub 2017 Jul 20.
MAbs. 2017.
PMID: 28726542
Free PMC article.
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Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody.
Singh S, Kroe-Barrett RR, Canada KA, Zhu X, Sepulveda E, Wu H, He Y, Raymond EL, Ahlberg J, Frego LE, Amodeo LM, Catron KM, Presky DH, Hanke JH.
Singh S, et al. Among authors: canada ka.
MAbs. 2015;7(4):778-91. doi: 10.1080/19420862.2015.1032491. Epub 2015 Apr 23.
MAbs. 2015.
PMID: 25905918
Free PMC article.
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Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.
Canada KA, Iwashita S, Shim H, Wood TK.
Canada KA, et al.
J Bacteriol. 2002 Jan;184(2):344-9. doi: 10.1128/JB.184.2.344-349.2002.
J Bacteriol. 2002.
PMID: 11751810
Free PMC article.
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Rhizosphere competitiveness of trichloroethylene-degrading, poplar-colonizing recombinant bacteria.
Shim H, Chauhan S, Ryoo D, Bowers K, Thomas SM, Canada KA, Burken JG, Wood TK.
Shim H, et al. Among authors: canada ka.
Appl Environ Microbiol. 2000 Nov;66(11):4673-8. doi: 10.1128/AEM.66.11.4673-4678.2000.
Appl Environ Microbiol. 2000.
PMID: 11055909
Free PMC article.
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