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Spiro[(dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)]-based cytotoxic agents: structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain.
Gomez-Monterrey I, Campiglia P, Carotenuto A, Stiuso P, Bertamino A, Sala M, Aquino C, Grieco P, Morello S, Pinto A, Ianelli P, Novellino E. Gomez-Monterrey I, et al. Among authors: campiglia p. J Med Chem. 2008 May 22;51(10):2924-32. doi: 10.1021/jm7013056. Epub 2008 Apr 23. J Med Chem. 2008. PMID: 18429610
New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide.
Grieco P, Carotenuto A, Campiglia P, Gomez-Monterrey I, Auriemma L, Sala M, Marcozzi C, d'Emmanuele di Villa Bianca R, Brancaccio D, Rovero P, Santicioli P, Meini S, Maggi CA, Novellino E. Grieco P, et al. Among authors: campiglia p. J Med Chem. 2009 Jul 9;52(13):3927-40. doi: 10.1021/jm900148c. J Med Chem. 2009. PMID: 19432421
Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives.
Bertamino A, Aquino C, Sala M, Simone Nd, Mattia CA, Erra L, Musella S, Iannelli P, Carotenuto A, Grieco P, Novellino E, Campiglia P, Gomez-Monterrey I. Bertamino A, et al. Among authors: campiglia p. Bioorg Med Chem. 2010 Jun 15;18(12):4328-37. doi: 10.1016/j.bmc.2010.04.079. Epub 2010 Apr 29. Bioorg Med Chem. 2010. PMID: 20483620
A novel quinone-based derivative (DTNQ-Pro) induces apoptotic death via modulation of heat shock protein expression in Caco-2 cells.
Gomez-Monterrey I, Campiglia P, Bertamino A, Aquino C, Sala M, Grieco P, Dicitore A, Vanacore D, Porta A, Maresca B, Novellino E, Stiuso P. Gomez-Monterrey I, et al. Among authors: campiglia p. Br J Pharmacol. 2010 Jun;160(4):931-40. doi: 10.1111/j.1476-5381.2010.00718.x. Br J Pharmacol. 2010. PMID: 20590589 Free PMC article.
Heat shock protein 90 inhibitors as therapeutic agents.
Gomez-Monterrey I, Sala M, Musella S, Campiglia P. Gomez-Monterrey I, et al. Among authors: campiglia p. Recent Pat Anticancer Drug Discov. 2012 Sep;7(3):313-36. doi: 10.2174/157489212801820066. Recent Pat Anticancer Drug Discov. 2012. PMID: 22338602 Review.
258 results