Campagnaro GD - Search Results

1

Structure-Activity Relationship Exploration of 3'-Deoxy-7-deazapurine Nucleoside Analogues as Anti-Trypanosoma brucei Agents.

Hulpia F, Campagnaro GD, Alzahrani KJ, Alfayez IA, Ungogo MA, Mabille D, Maes L, de Koning HP, Caljon G, Van Calenbergh S. Hulpia F, et al. Among authors: campagnaro gd. ACS Infect Dis. 2020 Aug 14;6(8):2045-2056. doi: 10.1021/acsinfecdis.0c00105. Epub 2020 Jul 8. ACS Infect Dis. 2020. PMID: 32568511

2

Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity.

Hulpia F, Campagnaro GD, Scortichini M, Van Hecke K, Maes L, de Koning HP, Caljon G, Van Calenbergh S. Hulpia F, et al. Among authors: campagnaro gd. Eur J Med Chem. 2019 Feb 15;164:689-705. doi: 10.1016/j.ejmech.2018.12.050. Epub 2018 Dec 21. Eur J Med Chem. 2019. PMID: 30677668

3

Trypanosoma brucei bloodstream forms express highly specific and separate transporters for adenine and hypoxanthine; evidence for a new protozoan purine transporter family?

Campagnaro GD, Alzahrani KJ, Munday JC, De Koning HP. Campagnaro GD, et al. Mol Biochem Parasitol. 2018 Mar;220:46-56. doi: 10.1016/j.molbiopara.2018.01.005. Epub 2018 Jan 31. Mol Biochem Parasitol. 2018. PMID: 29371154

4

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness.

Hulpia F, Mabille D, Campagnaro GD, Schumann G, Maes L, Roditi I, Hofer A, de Koning HP, Caljon G, Van Calenbergh S. Hulpia F, et al. Among authors: campagnaro gd. Nat Commun. 2019 Dec 5;10(1):5564. doi: 10.1038/s41467-019-13522-6. Nat Commun. 2019. PMID: 31804484 Free PMC article.

5

C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.

Hulpia F, Bouton J, Campagnaro GD, Alfayez IA, Mabille D, Maes L, de Koning HP, Caljon G, Van Calenbergh S. Hulpia F, et al. Among authors: campagnaro gd. Eur J Med Chem. 2020 Feb 15;188:112018. doi: 10.1016/j.ejmech.2019.112018. Epub 2020 Jan 3. Eur J Med Chem. 2020. PMID: 31931339

6

Cloning and characterisation of the Equilibrative Nucleoside Transporter family of Trypanosoma cruzi: ultra-high affinity and selectivity to survive in the intracellular niche.

Campagnaro GD, de Freitas Nascimento J, Girard RBM, Silber AM, de Koning HP. Campagnaro GD, et al. Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2750-2763. doi: 10.1016/j.bbagen.2018.08.015. Epub 2018 Aug 24. Biochim Biophys Acta Gen Subj. 2018. PMID: 30251664

7

Purine and pyrimidine transporters of pathogenic protozoa - conduits for therapeutic agents.

Campagnaro GD, de Koning HP. Campagnaro GD, et al. Med Res Rev. 2020 Sep;40(5):1679-1714. doi: 10.1002/med.21667. Epub 2020 Mar 7. Med Res Rev. 2020. PMID: 32144812 Review.

8

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.

Alghamdi AH, Munday JC, Campagnaro GD, Gurvic D, Svensson F, Okpara CE, Kumar A, Quintana J, Martin Abril ME, Milić P, Watson L, Paape D, Settimo L, Dimitriou A, Wielinska J, Smart G, Anderson LF, Woodley CM, Kelly SPY, Ibrahim HM, Hulpia F, Al-Salabi MI, Eze AA, Sprenger T, Teka IA, Gudin S, Weyand S, Field M, Dardonville C, Tidwell RR, Carrington M, O'Neill P, Boykin DW, Zachariae U, De Koning HP. Alghamdi AH, et al. Among authors: campagnaro gd. Elife. 2020 Aug 11;9:e56416. doi: 10.7554/eLife.56416. Elife. 2020. PMID: 32762841 Free PMC article.

9

Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential.

Carruthers LV, Munday JC, Ebiloma GU, Steketee P, Jayaraman S, Campagnaro GD, Ungogo MA, Lemgruber L, Donachie AM, Rowan TG, Peter R, Morrison LJ, Barrett MP, De Koning HP. Carruthers LV, et al. Among authors: campagnaro gd. Mol Microbiol. 2021 Aug;116(2):564-588. doi: 10.1111/mmi.14733. Epub 2021 May 18. Mol Microbiol. 2021. PMID: 33932053 Free article.

10

A Toxoplasma gondii Oxopurine Transporter Binds Nucleobases and Nucleosides Using Different Binding Modes.

Campagnaro GD, Elati HAA, Balaska S, Martin Abril ME, Natto MJ, Hulpia F, Lee K, Sheiner L, Van Calenbergh S, de Koning HP. Campagnaro GD, et al. Int J Mol Sci. 2022 Jan 10;23(2):710. doi: 10.3390/ijms23020710. Int J Mol Sci. 2022. PMID: 35054895 Free PMC article.

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