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EXO1 protects BRCA1-deficient cells against toxic DNA lesions.
van de Kooij B, Schreuder A, Pavani R, Garzero V, Uruci S, Wendel TJ, van Hoeck A, San Martin Alonso M, Everts M, Koerse D, Callen E, Boom J, Mei H, Cuppen E, Luijsterburg MS, van Vugt MATM, Nussenzweig A, van Attikum H, Noordermeer SM. van de Kooij B, et al. Among authors: callen e. Mol Cell. 2024 Feb 15;84(4):659-674.e7. doi: 10.1016/j.molcel.2023.12.039. Epub 2024 Jan 23. Mol Cell. 2024. PMID: 38266640 Free article.
BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. Bunting SF, et al. Among authors: callen e. Mol Cell. 2012 Apr 27;46(2):125-35. doi: 10.1016/j.molcel.2012.02.015. Epub 2012 Mar 22. Mol Cell. 2012. PMID: 22445484 Free PMC article.
S1-END-seq reveals DNA secondary structures in human cells.
Matos-Rodrigues G, van Wietmarschen N, Wu W, Tripathi V, Koussa NC, Pavani R, Nathan WJ, Callen E, Belinky F, Mohammed A, Napierala M, Usdin K, Ansari AZ, Mirkin SM, Nussenzweig A. Matos-Rodrigues G, et al. Among authors: callen e. Mol Cell. 2022 Oct 6;82(19):3538-3552.e5. doi: 10.1016/j.molcel.2022.08.007. Epub 2022 Sep 7. Mol Cell. 2022. PMID: 36075220 Free PMC article.
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells.
van de Kooij B, Schreuder A, Pavani RS, Garzero V, Van Hoeck A, San Martin Alonso M, Koerse D, Wendel TJ, Callen E, Boom J, Mei H, Cuppen E, Nussenzweig A, van Attikum H, Noordermeer SM. van de Kooij B, et al. Among authors: callen e. bioRxiv [Preprint]. 2023 Feb 24:2023.02.24.529205. doi: 10.1101/2023.02.24.529205. bioRxiv. 2023. PMID: 37720033 Free PMC article. Preprint.
53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Callen E, Zong D, Wu W, Wong N, Stanlie A, Ishikawa M, Pavani R, Dumitrache LC, Byrum AK, Mendez-Dorantes C, Martinez P, Canela A, Maman Y, Day A, Kruhlak MJ, Blasco MA, Stark JM, Mosammaparast N, McKinnon PJ, Nussenzweig A. Callen E, et al. Mol Cell. 2020 Jan 2;77(1):26-38.e7. doi: 10.1016/j.molcel.2019.09.024. Epub 2019 Oct 22. Mol Cell. 2020. PMID: 31653568 Free PMC article.
Identification of early replicating fragile sites that contribute to genome instability.
Barlow JH, Faryabi RB, Callén E, Wong N, Malhowski A, Chen HT, Gutierrez-Cruz G, Sun HW, McKinnon P, Wright G, Casellas R, Robbiani DF, Staudt L, Fernandez-Capetillo O, Nussenzweig A. Barlow JH, et al. Among authors: callen e. Cell. 2013 Jan 31;152(3):620-32. doi: 10.1016/j.cell.2013.01.006. Epub 2013 Jan 24. Cell. 2013. PMID: 23352430 Free PMC article. Review.
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, Ge K, Alt FW, Fernandez-Capetillo O, Nussenzweig MC, Nussenzweig A. Callen E, et al. Cell. 2013 Jun 6;153(6):1266-80. doi: 10.1016/j.cell.2013.05.023. Epub 2013 May 30. Cell. 2013. PMID: 23727112 Free PMC article.
BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Zong D, Adam S, Wang Y, Sasanuma H, Callén E, Murga M, Day A, Kruhlak MJ, Wong N, Munro M, Ray Chaudhuri A, Karim B, Xia B, Takeda S, Johnson N, Durocher D, Nussenzweig A. Zong D, et al. Among authors: callen e. Mol Cell. 2019 Mar 21;73(6):1267-1281.e7. doi: 10.1016/j.molcel.2018.12.010. Epub 2019 Jan 28. Mol Cell. 2019. PMID: 30704900 Free PMC article.
109 results