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Endothelial PFKFB3 plays a critical role in angiogenesis.
Xu Y, An X, Guo X, Habtetsion TG, Wang Y, Xu X, Kandala S, Li Q, Li H, Zhang C, Caldwell RB, Fulton DJ, Su Y, Hoda MN, Zhou G, Wu C, Huo Y. Xu Y, et al. Among authors: caldwell rb. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1231-9. doi: 10.1161/ATVBAHA.113.303041. Epub 2014 Apr 3. Arterioscler Thromb Vasc Biol. 2014. PMID: 24700124 Free PMC article.
Obesity-induced vascular inflammation involves elevated arginase activity.
Yao L, Bhatta A, Xu Z, Chen J, Toque HA, Chen Y, Xu Y, Bagi Z, Lucas R, Huo Y, Caldwell RB, Caldwell RW. Yao L, et al. Among authors: caldwell rb, caldwell rw. Am J Physiol Regul Integr Comp Physiol. 2017 Nov 1;313(5):R560-R571. doi: 10.1152/ajpregu.00529.2016. Epub 2017 Aug 23. Am J Physiol Regul Integr Comp Physiol. 2017. PMID: 28835451 Free PMC article.
Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.
Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton DJ, Weintraub NL, Caldwell RB, Zhang W, Wu C, Liu XL, Chen JF, Ahmad A, Kaddour-Djebbar I, Al-Shabrawey M, Li Q, Jiang X, Sun Y, Sodhi A, Smith L, Hong M, Huo Y. Liu Z, et al. Among authors: caldwell rb. Nat Commun. 2017 Sep 19;8(1):584. doi: 10.1038/s41467-017-00551-2. Nat Commun. 2017. PMID: 28928465 Free PMC article.
Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses.
Fouda AY, Xu Z, Shosha E, Lemtalsi T, Chen J, Toque HA, Tritz R, Cui X, Stansfield BK, Huo Y, Rodriguez PC, Smith SB, Caldwell RW, Narayanan SP, Caldwell RB. Fouda AY, et al. Among authors: caldwell rb, caldwell rw. Cell Death Dis. 2018 Sep 25;9(10):1001. doi: 10.1038/s41419-018-1051-6. Cell Death Dis. 2018. PMID: 30254218 Free PMC article.
208 results