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The anti-mitotic agents PTC-028 and PTC596 display potent activity in pre-clinical models of multiple myeloma but challenge the role of BMI-1 as an essential tumour gene.
Bolomsky A, Muller J, Stangelberger K, Lejeune M, Duray E, Breid H, Vrancken L, Pfeiffer C, Hübl W, Willheim M, Weetall M, Branstrom A, Zojer N, Caers J, Ludwig H. Bolomsky A, et al. Among authors: caers j. Br J Haematol. 2020 Sep;190(6):877-890. doi: 10.1111/bjh.16595. Epub 2020 Mar 30. Br J Haematol. 2020. PMID: 32232850 Free article.
Multiple myeloma--an update on diagnosis and treatment.
Caers J, Vande broek I, De Raeve H, Michaux L, Trullemans F, Schots R, Van Camp B, Vanderkerken K. Caers J, et al. Eur J Haematol. 2008 Nov;81(5):329-43. doi: 10.1111/j.1600-0609.2008.01127.x. Epub 2008 Sep 13. Eur J Haematol. 2008. PMID: 18637123 Review.
Cellular immunotherapy in multiple myeloma: lessons from preclinical models.
Binsfeld M, Fostier K, Muller J, Baron F, Schots R, Beguin Y, Heusschen R, Caers J. Binsfeld M, et al. Among authors: caers j. Biochim Biophys Acta. 2014 Dec;1846(2):392-404. doi: 10.1016/j.bbcan.2014.08.001. Epub 2014 Aug 7. Biochim Biophys Acta. 2014. PMID: 25109893 Free article. Review.
The Changing Landscape of Smoldering Multiple Myeloma: A European Perspective.
Caers J, Fernández de Larrea C, Leleu X, Heusschen R, Zojer N, Decaux O, Kastritis E, Minnema M, Jurczyszyn A, Beguin Y, Wäsch R, Palumbo A, Dimopoulos M, Mateos MV, Ludwig H, Engelhardt M. Caers J, et al. Oncologist. 2016 Mar;21(3):333-42. doi: 10.1634/theoncologist.2015-0303. Epub 2016 Feb 26. Oncologist. 2016. PMID: 26921288 Free PMC article. Review.
From transplant to novel cellular therapies in multiple myeloma: European Myeloma Network guidelines and future perspectives.
Gay F, Engelhardt M, Terpos E, Wäsch R, Giaccone L, Auner HW, Caers J, Gramatzki M, van de Donk N, Oliva S, Zamagni E, Garderet L, Straka C, Hajek R, Ludwig H, Einsele H, Dimopoulos M, Boccadoro M, Kröger N, Cavo M, Goldschmidt H, Bruno B, Sonneveld P. Gay F, et al. Among authors: caers j. Haematologica. 2018 Feb;103(2):197-211. doi: 10.3324/haematol.2017.174573. Epub 2017 Dec 7. Haematologica. 2018. PMID: 29217780 Free PMC article. Review.
127 results