Cadiñanos J - Search Results

1

Splicing-directed therapy in a new mouse model of human accelerated aging.

Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, De Sandre-Giovannoli A, Freije JM, Lévy N, López-Otín C. Osorio FG, et al. Among authors: cadinanos j. Sci Transl Med. 2011 Oct 26;3(106):106ra107. doi: 10.1126/scitranslmed.3002847. Sci Transl Med. 2011. PMID: 22030750

2

Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.

Freije JM, Blay P, Pendás AM, Cadiñanos J, Crespo P, López-Otín C. Freije JM, et al. Among authors: cadinanos j. Genomics. 1999 Jun 15;58(3):270-80. doi: 10.1006/geno.1999.5834. Genomics. 1999. PMID: 10373325

3

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

Pendás AM, Zhou Z, Cadiñanos J, Freije JM, Wang J, Hultenby K, Astudillo A, Wernerson A, Rodríguez F, Tryggvason K, López-Otín C. Pendás AM, et al. Among authors: cadinanos j. Nat Genet. 2002 May;31(1):94-9. doi: 10.1038/ng871. Epub 2002 Apr 1. Nat Genet. 2002. PMID: 11923874

4

Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans.

Cadiñanos J, Schmidt WK, Fueyo A, Varela I, López-Otín C, Freije JM. Cadiñanos J, et al. Biochem J. 2003 Mar 15;370(Pt 3):1047-54. doi: 10.1042/BJ20021514. Biochem J. 2003. PMID: 12487630 Free PMC article.

5

AtFACE-2, a functional prenylated protein protease from Arabidopsis thaliana related to mammalian Ras-converting enzymes.

Cadiñanos J, Varela I, Mandel DA, Schmidt WK, Díaz-Perales A, López-Otín C, Freije JM. Cadiñanos J, et al. J Biol Chem. 2003 Oct 24;278(43):42091-7. doi: 10.1074/jbc.M306700200. Epub 2003 Aug 19. J Biol Chem. 2003. PMID: 12928436 Free article.

6

Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors.

Navarro CL, Cadiñanos J, De Sandre-Giovannoli A, Bernard R, Courrier S, Boccaccio I, Boyer A, Kleijer WJ, Wagner A, Giuliano F, Beemer FA, Freije JM, Cau P, Hennekam RC, López-Otín C, Badens C, Lévy N. Navarro CL, et al. Among authors: cadinanos j. Hum Mol Genet. 2005 Jun 1;14(11):1503-13. doi: 10.1093/hmg/ddi159. Epub 2005 Apr 20. Hum Mol Genet. 2005. PMID: 15843403

7

Genomic instability in laminopathy-based premature aging.

Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang JD, Li KM, Chau PY, Chen DJ, Pei D, Pendas AM, Cadiñanos J, López-Otín C, Tse HF, Hutchison C, Chen J, Cao Y, Cheah KS, Tryggvason K, Zhou Z. Liu B, et al. Among authors: cadinanos j. Nat Med. 2005 Jul;11(7):780-5. doi: 10.1038/nm1266. Epub 2005 Jun 26. Nat Med. 2005. PMID: 15980864

8

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

Varela I, Cadiñanos J, Pendás AM, Gutiérrez-Fernández A, Folgueras AR, Sánchez LM, Zhou Z, Rodríguez FJ, Stewart CL, Vega JA, Tryggvason K, Freije JM, López-Otín C. Varela I, et al. Among authors: cadinanos j. Nature. 2005 Sep 22;437(7058):564-8. doi: 10.1038/nature04019. Epub 2005 Aug 3. Nature. 2005. PMID: 16079796

9

From immature lamin to premature aging: molecular pathways and therapeutic opportunities.

Cadiñanos J, Varela I, López-Otín C, Freije JM. Cadiñanos J, et al. Cell Cycle. 2005 Dec;4(12):1732-5. doi: 10.4161/cc.4.12.2202. Epub 2005 Dec 23. Cell Cycle. 2005. PMID: 16258283

10

Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions.

Ramírez CL, Cadiñanos J, Varela I, Freije JM, López-Otín C. Ramírez CL, et al. Among authors: cadinanos j. Cell Mol Life Sci. 2007 Jan;64(2):155-70. doi: 10.1007/s00018-006-6349-3. Cell Mol Life Sci. 2007. PMID: 17131053 Review.

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