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Triple Vectors Expand AAV Transfer Capacity in the Retina.
Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, Rossi S, Simonelli F, Naggert JK, Cacchiarelli D, Auricchio A. Maddalena A, et al. Among authors: cacchiarelli d. Mol Ther. 2018 Feb 7;26(2):524-541. doi: 10.1016/j.ymthe.2017.11.019. Epub 2017 Dec 5. Mol Ther. 2018. PMID: 29292161 Free PMC article.
Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.
Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C. Cacchiarelli D, et al. Cell Syst. 2018 Sep 26;7(3):258-268.e3. doi: 10.1016/j.cels.2018.07.006. Epub 2018 Sep 5. Cell Syst. 2018. PMID: 30195438 Free article.
A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high-grade serous ovarian cancer.
Lo Riso P, Villa CE, Gasparoni G, Vingiani A, Luongo R, Manfredi A, Jungmann A, Bertolotti A, Borgo F, Garbi A, Lupia M, Laise P, Das V, Pruneri G, Viale G, Colombo N, Manzo T, Nezi L, Cavallaro U, Cacchiarelli D, Walter J, Testa G. Lo Riso P, et al. Among authors: cacchiarelli d. Genome Med. 2020 Oct 30;12(1):94. doi: 10.1186/s13073-020-00786-7. Genome Med. 2020. PMID: 33121525 Free PMC article.
The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs.
Michielin F, Giobbe GG, Luni C, Hu Q, Maroni I, Orford MR, Manfredi A, Di Filippo L, David AL, Cacchiarelli D, De Coppi P, Eaton S, Elvassore N. Michielin F, et al. Among authors: cacchiarelli d. Cell Rep. 2020 Dec 1;33(9):108453. doi: 10.1016/j.celrep.2020.108453. Cell Rep. 2020. PMID: 33264615 Free PMC article.
YAP contributes to DNA methylation remodeling upon mouse embryonic stem cell differentiation.
Passaro F, De Martino I, Zambelli F, Di Benedetto G, Barbato M, D'Erchia AM, Manzari C, Pesole G, Mutarelli M, Cacchiarelli D, Antonini D, Parisi S, Russo T. Passaro F, et al. Among authors: cacchiarelli d, d erchia am. J Biol Chem. 2021 Jan-Jun;296:100138. doi: 10.1074/jbc.RA120.015896. Epub 2020 Dec 6. J Biol Chem. 2021. PMID: 33268382 Free PMC article.
Therapeutic homology-independent targeted integration in retina and liver.
Tornabene P, Ferla R, Llado-Santaeularia M, Centrulo M, Dell'Anno M, Esposito F, Marrocco E, Pone E, Minopoli R, Iodice C, Nusco E, Rossi S, Lyubenova H, Manfredi A, Di Filippo L, Iuliano A, Torella A, Piluso G, Musacchia F, Surace EM, Cacchiarelli D, Nigro V, Auricchio A. Tornabene P, et al. Among authors: cacchiarelli d. Nat Commun. 2022 Apr 12;13(1):1963. doi: 10.1038/s41467-022-29550-8. Nat Commun. 2022. PMID: 35414130 Free PMC article.
Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients.
Grimaldi A, Panariello F, Annunziata P, Giuliano T, Daniele M, Pierri B, Colantuono C, Salvi M, Bouché V, Manfredi A, Cuomo MC, Di Concilio D, Tiberio C, Fiorenza M, Portella G, Cimmino I, Sorrentino A, Fusco G, Granata MR, Cerino P, Limone A, Atripaldi L, Ballabio A, Cacchiarelli D. Grimaldi A, et al. Among authors: cacchiarelli d. Genome Med. 2022 Aug 12;14(1):90. doi: 10.1186/s13073-022-01098-8. Genome Med. 2022. PMID: 35962405 Free PMC article.
3D ECM-rich environment sustains the identity of naive human iPSCs.
Cesare E, Urciuolo A, Stuart HT, Torchio E, Gesualdo A, Laterza C, Gagliano O, Martewicz S, Cui M, Manfredi A, Di Filippo L, Sabatelli P, Squarzoni S, Zorzan I, Betto RM, Martello G, Cacchiarelli D, Luni C, Elvassore N. Cesare E, et al. Among authors: cacchiarelli d. Cell Stem Cell. 2022 Dec 1;29(12):1703-1717.e7. doi: 10.1016/j.stem.2022.11.011. Cell Stem Cell. 2022. PMID: 36459970 Free article.
57 results