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An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen.
Limonta-Fernández M, Chinea-Santiago G, Martín-Dunn AM, Gonzalez-Roche D, Bequet-Romero M, Marquez-Perera G, González-Moya I, Canaan-Haden-Ayala C, Cabrales-Rico A, Espinosa-Rodríguez LA, Ramos-Gómez Y, Andujar-Martínez I, González-López LJ, de la Iglesia MP, Zamora-Sanchez J, Cruz-Sui O, Lemos-Pérez G, Cabrera-Herrera G, Valdes-Hernández J, Martinez-Diaz E, Pimentel-Vazquez E, Ayala-Avila M, Guillén-Nieto G. Limonta-Fernández M, et al. Among authors: cabrales rico a. N Biotechnol. 2022 Dec 25;72:11-21. doi: 10.1016/j.nbt.2022.08.002. Epub 2022 Aug 8. N Biotechnol. 2022. PMID: 35953030 Free PMC article.
d-Amino acid substitutions and dimerization increase the biological activity and stability of an IL-15 antagonist peptide.
Rodríguez-Álvarez Y, Cabrales-Rico A, Diago-Abreu D, Correa-Arguelles E, Reyes-Acosta O, Puente-Pérez P, Pichardo-Díaz D, Urquiza-Noa D, Hernández-Santana A, Garay-Pérez HE. Rodríguez-Álvarez Y, et al. Among authors: cabrales rico a. J Pept Sci. 2021 Mar;27(3):e3293. doi: 10.1002/psc.3293. Epub 2020 Dec 16. J Pept Sci. 2021. PMID: 33331098
In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays.
Rodríguez-Álvarez Y, Cabrales-Rico A, Perera-Pintado A, Prats-Capote A, Garay-Pérez HE, Reyes-Acosta O, Pérez-García E, Chico-Capote A, Santos-Savio A. Rodríguez-Álvarez Y, et al. Among authors: cabrales rico a. J Pept Sci. 2018 Jun;24(4-5):e3078. doi: 10.1002/psc.3078. Epub 2018 Apr 15. J Pept Sci. 2018. PMID: 29656472
Antitumor efficacy, pharmacokinetic and biodistribution studies of the anticancer peptide CIGB-552 in mouse models.
Vallespí MG, Pimentel G, Cabrales-Rico A, Garza J, Oliva B, Mendoza O, Gomez Y, Basaco T, Sánchez I, Calderón C, Rodriguez JC, Markelova MR, Fichtner I, Astrada S, Bollati-Fogolín M, Garay HE, Reyes O. Vallespí MG, et al. Among authors: cabrales rico a. J Pept Sci. 2014 Nov;20(11):850-9. doi: 10.1002/psc.2676. Epub 2014 Jul 20. J Pept Sci. 2014. PMID: 25044757
Development and validation of a bioanalytical method based on LC-MS/MS analysis for the quantitation of CIGB-814 peptide in plasma from Rheumatoid Arthritis patients.
Cabrales-Rico A, Ramos Y, Besada V, Del Carmen Domínguez M, Lorenzo N, García O, Alexis J, Prada D, Reyes Y, López AM, Masforrol Y, Garay H, González LJ. Cabrales-Rico A, et al. J Pharm Biomed Anal. 2017 Sep 5;143:130-140. doi: 10.1016/j.jpba.2017.05.030. Epub 2017 Jun 1. J Pharm Biomed Anal. 2017. PMID: 28595106