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Primary endothelial cell-specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia.
Bartoszewski R, Moszyńska A, Serocki M, Cabaj A, Polten A, Ochocka R, Dell'Italia L, Bartoszewska S, Króliczewski J, Dąbrowski M, Collawn JF. Bartoszewski R, et al. Among authors: cabaj a. FASEB J. 2019 Jul;33(7):7929-7941. doi: 10.1096/fj.201802650RR. Epub 2019 Mar 27. FASEB J. 2019. PMID: 30917010 Free PMC article.
During hypoxia, a cellular adaptive response activates hypoxia-inducible factors (HIFs; HIF-1 and HIF-2) that respond to low tissue-oxygen levels and induce the expression of a number of genes that promote angiogenesis, energy metabolism, and cell survival. ...-Bart …
During hypoxia, a cellular adaptive response activates hypoxia-inducible factors (HIFs; HIF-1 and HIF-2) that respond to low tissue-o …
miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response.
Bartoszewska S, Cabaj A, Dąbrowski M, Collawn JF, Bartoszewski R. Bartoszewska S, et al. Among authors: cabaj a. FASEB J. 2019 Oct;33(10):11541-11554. doi: 10.1096/fj.201900600RR. Epub 2019 Jul 17. FASEB J. 2019. PMID: 31314593 Free PMC article.
X-box-binding protein 1 (XBP1) is one component of the UPR and is a proadaptive transcription factor that is subject to transcriptional, post-transcriptional, and post-translational control. ...We showed that miR-34c-5p directly attenuates spliced XBP1 (XBP1s) mRNA levels …
X-box-binding protein 1 (XBP1) is one component of the UPR and is a proadaptive transcription factor that is subject to transcription …
Genome-wide mRNA profiling identifies RCAN1 and GADD45A as regulators of the transitional switch from survival to apoptosis during ER stress.
Bartoszewski R, Gebert M, Janaszak-Jasiecka A, Cabaj A, Króliczewski J, Bartoszewska S, Sobolewska A, Crossman DK, Ochocka R, Kamysz W, Kalinowski L, Dąbrowski M, Collawn JF. Bartoszewski R, et al. Among authors: cabaj a. FEBS J. 2020 Jul;287(14):2923-2947. doi: 10.1111/febs.15195. Epub 2020 Jan 10. FEBS J. 2020. PMID: 31880863 Free article.
SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains.
Rzymski T, Mikula M, Żyłkiewicz E, Dreas A, Wiklik K, Gołas A, Wójcik K, Masiejczyk M, Wróbel A, Dolata I, Kitlińska A, Statkiewicz M, Kuklinska U, Goryca K, Sapała Ł, Grochowska A, Cabaj A, Szajewska-Skuta M, Gabor-Worwa E, Kucwaj K, Białas A, Radzimierski A, Combik M, Woyciechowski J, Mikulski M, Windak R, Ostrowski J, Brzózka K. Rzymski T, et al. Among authors: cabaj a. Oncotarget. 2017 May 16;8(20):33779-33795. doi: 10.18632/oncotarget.16810. Oncotarget. 2017. PMID: 28422713 Free PMC article.
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