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Once-Daily Subcutaneous Irisin Administration Mitigates Depression- and Anxiety-like Behavior in Young Mice.
Pignataro P, Dicarlo M, Suriano C, Sanesi L, Zerlotin R, Storlino G, Oranger A, Zecca C, Dell'Abate MT, Mori G, Grano M, Colucci S, Colaianni G. Pignataro P, et al. Int J Mol Sci. 2023 Apr 4;24(7):6715. doi: 10.3390/ijms24076715. Int J Mol Sci. 2023. PMID: 37047687 Free PMC article.
Moreover, a qRT-PCR assay was performed to analyze the impact of irisin treatment on Pgc-1alpha/FNDC5 expression in the brain. A significant reduction in immobility time in TST and FST was observed in irisin-treated mice. ...Overall, these results suggest that short-term s …
Moreover, a qRT-PCR assay was performed to analyze the impact of irisin treatment on Pgc-1alpha/FNDC5 expression in the brain. A sign …
Elevated Expression of ADAM10 in Skeletal Muscle of Patients with Idiopathic Inflammatory Myopathies Could Be Responsible for FNDC5/Irisin Unbalance.
Zerlotin R, Fornaro M, Errede M, Pignataro P, Suriano C, Ruggieri M, Colucci S, Iannone F, Grano M, Colaianni G. Zerlotin R, et al. Int J Mol Sci. 2023 Jan 27;24(3):2469. doi: 10.3390/ijms24032469. Int J Mol Sci. 2023. PMID: 36768791 Free PMC article.
Dermatomyositis (DM) and immune-mediated necrotizing myopathy (IMNM) are two rare diseases belonging to the group of idiopathic inflammatory myopathies (IIM). Muscle involvement in DM is characterized by perifascicular atrophy and poor myofiber necrosis, while IMNM is char …
Dermatomyositis (DM) and immune-mediated necrotizing myopathy (IMNM) are two rare diseases belonging to the group of idiopathic infla …
Irisin Modulates Inflammatory, Angiogenic, and Osteogenic Factors during Fracture Healing.
Oranger A, Zerlotin R, Buccoliero C, Sanesi L, Storlino G, Schipani E, Kozloff KM, Mori G, Colaianni G, Colucci S, Grano M. Oranger A, et al. Int J Mol Sci. 2023 Jan 17;24(3):1809. doi: 10.3390/ijms24031809. Int J Mol Sci. 2023. PMID: 36768133 Free PMC article.
Bone fractures are a widespread clinical event due to accidental falls and trauma or bone fragility; they also occur in association with various diseases and are common with aging. In the search for new therapeutic strategies, a crucial link between irisin and bone …
Bone fractures are a widespread clinical event due to accidental falls and trauma or bone fragility; they also occur in association with var …