C06 RR012512/RR/NCRR NIH HHS/United States[Grants and Funding] - Search Results

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Subject: C06 RR012512/RR/NCRR NIH HHS/United States[Grants - PubMed

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Results by year

Year	Number of Results
2006	1
2007	1
2008	4
2009	3
2010	5
2011	7
2012	4
2013	2
2014	3
2016	4
2019	4
2020	2
2021	2
2022	1
2024	0

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Design and discovery of a high affinity, selective and β-arrestin biased 5-HT₇ Receptor Agonist.

Onyameh EK, Ofori E, Bricker BA, Gonela UM, Eyunni SVK, Kang HJ, Voshavar C, Ablordeppey SY. Onyameh EK, et al. Med Chem Res. 2022 Feb;31(2):274-283. doi: 10.1007/s00044-021-02797-4. Epub 2021 Sep 23. Med Chem Res. 2022. PMID: 35340752 Free PMC article.

A Mechanistic Investigation on the Anticancer Properties of SYA013, a Homopiperazine Analogue of Haloperidol with Activity against Triple Negative Breast Cancer Cells.

Asong GM, Amissah F, Voshavar C, Nkembo AT, Ntantie E, Lamango NS, Ablordeppey SY. Asong GM, et al. ACS Omega. 2020 Dec 16;5(51):32907-32918. doi: 10.1021/acsomega.0c03495. eCollection 2020 Dec 29. ACS Omega. 2020. PMID: 33403252 Free PMC article.

A study of the structure-affinity relationship in SYA16263; is a D₂ receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice?

Onyameh EK, Bricker BA, Eyunni SVK, Voshavar C, Gonela UM, Ofori E, Jenkins A, Ablordeppey SY. Onyameh EK, et al. Bioorg Med Chem. 2021 Jan 15;30:115943. doi: 10.1016/j.bmc.2020.115943. Epub 2020 Dec 14. Bioorg Med Chem. 2021. PMID: 33338898 Free PMC article.

New analogs of SYA013 as sigma-2 ligands with anticancer activity.

Asong G, Zhu XY, Bricker B, Andey T, Amissah F, Lamango N, Ablordeppey SY. Asong G, et al. Bioorg Med Chem. 2019 Jun 15;27(12):2629-2636. doi: 10.1016/j.bmc.2019.04.012. Epub 2019 Apr 8. Bioorg Med Chem. 2019. PMID: 30987780 Free PMC article.

Copper-Catalyzed, Ceric Ammonium Nitrate Mediated N-Arylation of Amines.

Gonela UM, Ablordeppey SY. Gonela UM, et al. New J Chem. 2019 Feb 21;43(7):2861-2864. doi: 10.1039/C8NJ06145A. Epub 2019 Jan 17. New J Chem. 2019. PMID: 30886516 Free PMC article.

Evaluation of SYA16263 as a new potential antipsychotic agent without catalepsy.

Bricker BA, Peprah K, Kang HJ, Ablordeppey SY. Bricker BA, et al. Pharmacol Biochem Behav. 2019 Apr;179:55-62. doi: 10.1016/j.pbb.2019.02.003. Epub 2019 Feb 12. Pharmacol Biochem Behav. 2019. PMID: 30768942 Free PMC article.

SYA 013 analogs as moderately selective sigma-2 (σ₂) ligands: Structure-affinity relationship studies.

Al-Ghanim L, Zhu XY, Asong G, Ablordeppey SY. Al-Ghanim L, et al. Bioorg Med Chem. 2019 Jun 15;27(12):2421-2426. doi: 10.1016/j.bmc.2019.01.035. Epub 2019 Jan 31. Bioorg Med Chem. 2019. PMID: 30737135 Free PMC article.

Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors.

Ofori E, Zhu XY, Etukala JR, Bricker BA, Ablordeppey SY. Ofori E, et al. Bioorg Med Chem. 2016 Nov 15;24(22):5730-5740. doi: 10.1016/j.bmc.2016.09.019. Epub 2016 Sep 10. Bioorg Med Chem. 2016. PMID: 27717652 Free PMC article.

Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores.

Etukala JR, Zhu XY, Eyunni SV, Onyameh EK, Ofori E, Bricker BA, Kang HJ, Huang XP, Roth BL, Ablordeppey SY. Etukala JR, et al. Bioorg Med Chem. 2016 Aug 15;24(16):3671-9. doi: 10.1016/j.bmc.2016.06.011. Epub 2016 Jun 4. Bioorg Med Chem. 2016. PMID: 27364609 Free PMC article.

Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands.

Ofori E, Zhu XY, Etukala JR, Peprah K, Jordan KR, Adkins AA, Bricker BA, Kang HJ, Huang XP, Roth BL, Ablordeppey SY. Ofori E, et al. Bioorg Med Chem. 2016 Aug 15;24(16):3464-71. doi: 10.1016/j.bmc.2016.05.053. Epub 2016 May 27. Bioorg Med Chem. 2016. PMID: 27312422 Free PMC article.

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