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Oncogenic drivers dictate immune control of acute myeloid leukemia.
Austin RJ, Straube J, Halder R, Janardhanan Y, Bruedigam C, Witkowski M, Cooper L, Porter A, Braun M, Souza-Fonseca-Guimaraes F, Minnie SA, Cooper E, Jacquelin S, Song A, Bald T, Nakamura K, Hill GR, Aifantis I, Lane SW, Bywater MJ. Austin RJ, et al. Among authors: bywater mj. Nat Commun. 2023 Apr 14;14(1):2155. doi: 10.1038/s41467-023-37592-9. Nat Commun. 2023. PMID: 37059710 Free PMC article.
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia.
Vu T, Straube J, Porter AH, Bywater M, Song A, Ling V, Cooper L, Pali G, Bruedigam C, Jacquelin S, Green J, Magor G, Perkins A, Chalk AM, Walkley CR, Heidel FH, Mukhopadhyay P, Cloonan N, Gröschel S, Mallm JP, Fröhling S, Scholl C, Lane SW. Vu T, et al. Nat Commun. 2020 Jun 15;11(1):3021. doi: 10.1038/s41467-020-16840-2. Nat Commun. 2020. PMID: 32541670 Free PMC article.
Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin S, Straube J, Cooper L, Vu T, Song A, Bywater M, Baxter E, Heidecker M, Wackrow B, Porter A, Ling V, Green J, Austin R, Kazakoff S, Waddell N, Hesson LB, Pimanda JE, Stegelmann F, Bullinger L, Döhner K, Rampal RK, Heckl D, Hill GR, Lane SW. Jacquelin S, et al. Blood. 2018 Dec 27;132(26):2707-2721. doi: 10.1182/blood-2018-04-846220. Epub 2018 Oct 26. Blood. 2018. PMID: 30366920 Free article.
A knockout combination for MPN stem cells.
Bywater M, Lane SW. Bywater M, et al. J Exp Med. 2021 Feb 1;218(2):e20201884. doi: 10.1084/jem.20201884. J Exp Med. 2021. PMID: 33185683 Free PMC article.
Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations.
Austin RJ, Straube J, Bruedigam C, Pali G, Jacquelin S, Vu T, Green J, Gräsel J, Lansink L, Cooper L, Lee SJ, Chen NT, Lee CW, Haque A, Heidel FH, D'Andrea R, Hill GR, Mullally A, Milsom MD, Bywater M, Lane SW. Austin RJ, et al. Leukemia. 2020 Apr;34(4):1075-1089. doi: 10.1038/s41375-019-0638-y. Epub 2019 Nov 15. Leukemia. 2020. PMID: 31732720 Free PMC article.
Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW. Lefebure M, et al. Among authors: bywater m. Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581. Nat Commun. 2017. PMID: 28262675 Free PMC article.
Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation.
Diesch J, Bywater MJ, Sanij E, Cameron DP, Schierding W, Brajanovski N, Son J, Sornkom J, Hein N, Evers M, Pearson RB, McArthur GA, Ganley ARD, O'Sullivan JM, Hannan RD, Poortinga G. Diesch J, et al. Among authors: bywater mj. Commun Biol. 2019 Jan 28;2:39. doi: 10.1038/s42003-019-0284-y. eCollection 2019. Commun Biol. 2019. PMID: 30701204 Free PMC article.
57 results