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Iminosugars: A host-targeted approach to combat Flaviviridae infections.
Evans DeWald L, Starr C, Butters T, Treston A, Warfield KL. Evans DeWald L, et al. Among authors: butters t. Antiviral Res. 2020 Dec;184:104881. doi: 10.1016/j.antiviral.2020.104881. Epub 2020 Aug 5. Antiviral Res. 2020. PMID: 32768411 Free PMC article. Review.
An iminosugar with potent inhibition of dengue virus infection in vivo.
Perry ST, Buck MD, Plummer EM, Penmasta RA, Batra H, Stavale EJ, Warfield KL, Dwek RA, Butters TD, Alonzi DS, Lada SM, King K, Klose B, Ramstedt U, Shresta S. Perry ST, et al. Among authors: butters td. Antiviral Res. 2013 Apr;98(1):35-43. doi: 10.1016/j.antiviral.2013.01.004. Epub 2013 Jan 31. Antiviral Res. 2013. PMID: 23376501
Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses.
Chang J, Warren TK, Zhao X, Gill T, Guo F, Wang L, Comunale MA, Du Y, Alonzi DS, Yu W, Ye H, Liu F, Guo JT, Mehta A, Cuconati A, Butters TD, Bavari S, Xu X, Block TM. Chang J, et al. Among authors: butters td. Antiviral Res. 2013 Jun;98(3):432-40. doi: 10.1016/j.antiviral.2013.03.023. Epub 2013 Apr 8. Antiviral Res. 2013. PMID: 23578725 Free PMC article.
Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Sobala ŁF, Fernandes PZ, Hakki Z, Thompson AJ, Howe JD, Hill M, Zitzmann N, Davies S, Stamataki Z, Butters TD, Alonzi DS, Williams SJ, Davies GJ. Sobala ŁF, et al. Among authors: butters td. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29595-29601. doi: 10.1073/pnas.2013620117. Epub 2020 Nov 5. Proc Natl Acad Sci U S A. 2020. PMID: 33154157 Free PMC article.
Novel imino sugar α-glucosidase inhibitors as antiviral compounds.
Howe JD, Smith N, Lee MJ, Ardes-Guisot N, Vauzeilles B, Désiré J, Baron A, Blériot Y, Sollogoub M, Alonzi DS, Butters TD. Howe JD, et al. Among authors: butters td. Bioorg Med Chem. 2013 Aug 15;21(16):4831-8. doi: 10.1016/j.bmc.2013.03.014. Epub 2013 Mar 22. Bioorg Med Chem. 2013. PMID: 23582447
Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.
Chang J, Schul W, Butters TD, Yip A, Liu B, Goh A, Lakshminarayana SB, Alonzi D, Reinkensmeier G, Pan X, Qu X, Weidner JM, Wang L, Yu W, Borune N, Kinch MA, Rayahin JE, Moriarty R, Xu X, Shi PY, Guo JT, Block TM. Chang J, et al. Antiviral Res. 2011 Jan;89(1):26-34. doi: 10.1016/j.antiviral.2010.11.002. Epub 2010 Nov 10. Antiviral Res. 2011. PMID: 21073903 Free PMC article.
181 results