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GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao Y, Du Jiang P, Chao BN, Cagdas D, Kubo S, Balasubramaniyam A, Zhang Y, Shadur B, NaserEddin A, Folio LR, Schwarz B, Bohrnsen E, Zheng L, Lynberg M, Gottlieb S, Leney-Greene MA, Park AY, Tezcan I, Akdogan A, Gocmen R, Onder S, Rosenberg A, Soilleux EJ, Johnson E, Jackson PK, Demeter J, Chauvin SD, Paul F, Selbach M, Bulut H, Clatworthy MR, Tuong ZK, Zhang H, Stewart BJ, Bosio CM, Stepensky P, Clare S, Ganesan S, Pascall JC, Daumke O, Butcher GW, McMichael AJ, Simon AK, Lenardo MJ. Yao Y, et al. Among authors: butcher gw. J Exp Med. 2022 Jun 6;219(6):e20201405. doi: 10.1084/jem.20201405. Epub 2022 May 13. J Exp Med. 2022. PMID: 35551368 Free PMC article.
GIMAP6 is required for T cell maintenance and efficient autophagy in mice.
Pascall JC, Webb LMC, Eskelinen EL, Innocentin S, Attaf-Bouabdallah N, Butcher GW. Pascall JC, et al. Among authors: butcher gw. PLoS One. 2018 May 2;13(5):e0196504. doi: 10.1371/journal.pone.0196504. eCollection 2018. PLoS One. 2018. PMID: 29718959 Free PMC article.
The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein.
Wong VW, Saunders AE, Hutchings A, Pascall JC, Carter C, Bright NA, Walker SA, Ktistakis NT, Butcher GW. Wong VW, et al. Among authors: butcher gw. Self Nonself. 2010 Jul;1(3):259-268. doi: 10.4161/self.1.3.12819. Epub 2010 Jun 25. Self Nonself. 2010. PMID: 21487483 Free PMC article.
A natural hypomorphic variant of the apoptosis regulator Gimap4/IAN1.
Carter C, Dion C, Schnell S, Coadwell WJ, Graham M, Hepburn L, Morgan G, Hutchings A, Pascall JC, Jacobs H, Miller JR, Butcher GW. Carter C, et al. Among authors: butcher gw. J Immunol. 2007 Aug 1;179(3):1784-95. doi: 10.4049/jimmunol.179.3.1784. J Immunol. 2007. PMID: 17641045
Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.
Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, Khovananth K, Engel I, Sovath S, Lampe K, Laws E, Saunders A, Butcher GW, Kronenberg M, Steinbrecher K, Hildeman D, Grimes HL, Beutler B, Hoebe K. Barnes MJ, et al. Among authors: butcher gw. J Immunol. 2010 Apr 1;184(7):3743-54. doi: 10.4049/jimmunol.0903164. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190135 Free PMC article.
154 results