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Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.
Dumetz F, Imamura H, Sanders M, Seblova V, Myskova J, Pescher P, Vanaerschot M, Meehan CJ, Cuypers B, De Muylder G, Späth GF, Bussotti G, Vermeesch JR, Berriman M, Cotton JA, Volf P, Dujardin JC, Domagalska MA. Dumetz F, et al. Among authors: bussotti g. mBio. 2017 May 23;8(3):e00599-17. doi: 10.1128/mBio.00599-17. mBio. 2017. PMID: 28536289 Free PMC article.
Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani.
Prieto Barja P, Pescher P, Bussotti G, Dumetz F, Imamura H, Kedra D, Domagalska M, Chaumeau V, Himmelbauer H, Pages M, Sterkers Y, Dujardin JC, Notredame C, Späth GF. Prieto Barja P, et al. Among authors: bussotti g. Nat Ecol Evol. 2017 Dec;1(12):1961-1969. doi: 10.1038/s41559-017-0361-x. Epub 2017 Nov 6. Nat Ecol Evol. 2017. PMID: 29109466 Free article.
Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification.
Bussotti G, Gouzelou E, Côrtes Boité M, Kherachi I, Harrat Z, Eddaikra N, Mottram JC, Antoniou M, Christodoulou V, Bali A, Guerfali FZ, Laouini D, Mukhtar M, Dumetz F, Dujardin JC, Smirlis D, Lechat P, Pescher P, El Hamouchi A, Lemrani M, Chicharro C, Llanes-Acevedo IP, Botana L, Cruz I, Moreno J, Jeddi F, Aoun K, Bouratbine A, Cupolillo E, Späth GF. Bussotti G, et al. mBio. 2018 Nov 6;9(6):e01399-18. doi: 10.1128/mBio.01399-18. mBio. 2018. PMID: 30401775 Free PMC article.
The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress.
Zavala-Alvarado C, Sismeiro O, Legendre R, Varet H, Bussotti G, Bayram J, G Huete S, Rey G, Coppée JY, Picardeau M, Benaroudj N. Zavala-Alvarado C, et al. Among authors: bussotti g. PLoS Pathog. 2020 Oct 6;16(10):e1008904. doi: 10.1371/journal.ppat.1008904. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33021995 Free PMC article.
Colonization and genetic diversification processes of Leishmania infantum in the Americas.
Schwabl P, Boité MC, Bussotti G, Jacobs A, Andersson B, Moreira O, Freitas-Mesquita AL, Meyer-Fernandes JR, Telleria EL, Traub-Csekö Y, Vaselek S, Leštinová T, Volf P, Morgado FN, Porrozzi R, Llewellyn M, Späth GF, Cupolillo E. Schwabl P, et al. Among authors: bussotti g. Commun Biol. 2021 Jan 29;4(1):139. doi: 10.1038/s42003-021-01658-5. Commun Biol. 2021. PMID: 33514858 Free PMC article.
The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.
Zavala-Alvarado C, G Huete S, Vincent AT, Sismeiro O, Legendre R, Varet H, Bussotti G, Lorioux C, Lechat P, Coppée JY, Veyrier FJ, Picardeau M, Benaroudj N. Zavala-Alvarado C, et al. Among authors: bussotti g. PLoS Pathog. 2021 Dec 2;17(12):e1009087. doi: 10.1371/journal.ppat.1009087. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34855911 Free PMC article.
Genome instability drives epistatic adaptation in the human pathogen Leishmania.
Bussotti G, Piel L, Pescher P, Domagalska MA, Rajan KS, Cohen-Chalamish S, Doniger T, Hiregange DG, Myler PJ, Unger R, Michaeli S, Späth GF. Bussotti G, et al. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2113744118. doi: 10.1073/pnas.2113744118. Proc Natl Acad Sci U S A. 2021. PMID: 34903666 Free PMC article.
38 results