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Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. Among authors: burth p. ChemMedChem. 2015 Dec;10(12):2014-26. doi: 10.1002/cmdc.201500360. Epub 2015 Oct 5. ChemMedChem. 2015. PMID: 26434977 Free PMC article.
4-Bromo-2-(piperidin-1-yl)thiazol-5-yl-phenyl methanone (12b) inhibits Na+/K(+)-ATPase and Ras oncogene activity in cancer cells.
Lefranc F, Xu Z, Burth P, Mathieu V, Revelant G, de Castro Faria MV, Noyon C, Garcia DG, Dufour D, Bruyère C, Gonçalves-de-Albuquerque CF, Van Antwerpen P, Rogister B, Hesse S, Kirsch G, Kiss R. Lefranc F, et al. Among authors: burth p. Eur J Med Chem. 2013 May;63:213-23. doi: 10.1016/j.ejmech.2013.01.046. Epub 2013 Feb 16. Eur J Med Chem. 2013. PMID: 23474907
Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Kälin RE, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. Among authors: burth p. Eur J Med Chem. 2015 Oct 20;103:226-37. doi: 10.1016/j.ejmech.2015.08.047. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26360047 Free PMC article.
Antileukemic Properties of Sesquiterpene Lactones: A Systematic Review.
da Silva Castro E, Alves Antunes LA, Revoredo Lobo JF, Ratcliffe NA, Borges RM, Rocha L, Burth P, Fonte Amorim LM. da Silva Castro E, et al. Among authors: burth p. Anticancer Agents Med Chem. 2018;18(3):323-334. doi: 10.2174/1871520617666170918130126. Anticancer Agents Med Chem. 2018. PMID: 28925880
The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor.
Garcia DG, Amorim LM, de Castro Faria MV, Freire AS, Santelli RE, Da Fonseca CO, Quirico-Santos T, Burth P. Garcia DG, et al. Among authors: burth p. Mol Cell Biochem. 2010 Dec;345(1-2):29-34. doi: 10.1007/s11010-010-0556-9. Epub 2010 Aug 6. Mol Cell Biochem. 2010. PMID: 20689980
Leptospira and inflammation.
Gonçalves-de-Albuquerque CF, Burth P, Silva AR, Younes-Ibrahim M, Castro-Faria-Neto HC, Castro-Faria MV. Gonçalves-de-Albuquerque CF, et al. Among authors: burth p. Mediators Inflamm. 2012;2012:317950. doi: 10.1155/2012/317950. Epub 2012 Oct 21. Mediators Inflamm. 2012. PMID: 23132959 Free PMC article.
Oleic acid induces lung injury in mice through activation of the ERK pathway.
Gonçalves-de-Albuquerque CF, Silva AR, Burth P, de Moraes IM, Oliveira FM, Younes-Ibrahim M, dos Santos Mda C, D'Ávila H, Bozza PT, Faria Neto HC, Faria MV. Gonçalves-de-Albuquerque CF, et al. Among authors: burth p. Mediators Inflamm. 2012;2012:956509. doi: 10.1155/2012/956509. Epub 2012 Nov 13. Mediators Inflamm. 2012. PMID: 23209347 Free PMC article.
37 results